Nicotinamide adenine dinucleotide (NAD+) is a coenzyme for redox reactions, making it
central to energy metabolism. NAD+ is also an essential cofactor for non-redox NAD+ …

The conceptual evolution of nicotinamide adenine dinucleotide (NAD+) from being seen as
a simple metabolic cofactor to a pivotal cosubstrate for proteins regulating metabolism and …

Mitochondria require nicotinamide adenine dinucleotide (NAD+) to carry out the
fundamental processes that fuel respiration and mediate cellular energy transduction …

Nicotinamide adenine dinucleotide, in its oxidized (NAD+) and reduced (NADH) forms, is a
reduction–oxidation (redox) co-factor and substrate for signalling enzymes that have …

The nicotinamide adenine dinucleotide (NAD+/NADH) pair is a cofactor in redox reactions
and is particularly critical in mitochondria as it connects substrate oxidation by the …

Nicotinamide adenine dinucleotide (NAD) is an important co-factor involved in numerous
physiological processes, including metabolism, post-translational protein modification, and …

The numerous biological roles of NAD+ are organized and coordinated via its
compartmentalization within cells. The spatial and temporal partitioning of this intermediary …

The coenzyme nicotinamide adenine dinucleotide (NAD+) has key roles in the regulation of
redox status and energy metabolism. NAD+ depletion is emerging as a major contributor to …

NAD+, the essential metabolite involved in multiple reactions such as the regulation of
cellular metabolism, energy production, DNA repair, mitophagy and autophagy …

Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under
stress. It has alternately been argued that NAD in mammalian mitochondria arises from …