Severity and outcomes of Omicron variant of SARS-CoV-2 compared to Delta variant and severity of Omicron sublineages: a systematic review and metanalysis
Objectives To compare severity and clinical outcomes from Omicron as compared with the
Delta variant and to compare outcomes between Omicron sublineages. Methods We …
Delta variant and to compare outcomes between Omicron sublineages. Methods We …
Severity of the Omicron SARS‐CoV‐2 variant compared with the previous lineages: A systematic review
M Arabi, Y Al‐Najjar, N Mhaimeed… - Journal of Cellular …, 2023 - Wiley Online Library
The Omicron variant was first detected in October 2021, which evolved from the original
SARS‐CoV‐2 strain and was found to possess many mutations. Immune evasion was one of …
SARS‐CoV‐2 strain and was found to possess many mutations. Immune evasion was one of …
Effectiveness of the pre-Omicron COVID-19 vaccines against Omicron in reducing infection, hospitalization, severity, and mortality compared to Delta and other …
P Paul, A El-Naas, O Hamad, MA Salameh… - Human Vaccines & …, 2023 - Taylor & Francis
Despite widespread mass rollout programs, the rapid spread of the SARS-CoV-2 Omicron
variant called into question the effectiveness of the existing vaccines against infection …
variant called into question the effectiveness of the existing vaccines against infection …
[HTML][HTML] Reduction of the risk of severe COVID-19 due to Omicron compared to Delta variant in Italy (November 2021–February 2022)
D Petrone, A Mateo-Urdiales, C Sacco… - International Journal of …, 2023 - Elsevier
Abstract Objectives During 2022, Omicron became the dominant SARS-CoV-2 variant in
Europe. This study aims to assess the impact of such variant on severe disease from SARS …
Europe. This study aims to assess the impact of such variant on severe disease from SARS …
[HTML][HTML] Positive selection underlies repeated knockout of ORF8 in SARS-CoV-2 evolution
C Wagner, KE Kistler, GA Perchetti, N Baker… - Nature …, 2024 - nature.com
Knockout of the ORF8 protein has repeatedly spread through the global viral population
during SARS-CoV-2 evolution. Here we use both regional and global pathogen sequencing …
during SARS-CoV-2 evolution. Here we use both regional and global pathogen sequencing …
Comparative hospitalization risk for SARS‐CoV‐2 Omicron and Delta variant infections, by variant predominance periods and patient‐level sequencing results, New …
SK Greene, A Levin‐Rector, NTT Kyaw… - Influenza and Other …, 2023 - Wiley Online Library
Background Comparing disease severity between SARS‐CoV‐2 variants among
populations with varied vaccination and infection histories can help characterize emerging …
populations with varied vaccination and infection histories can help characterize emerging …
Ecological and Evolutionary Insights About Emerging Infectious Diseases from the COVID-19 Pandemic
AM Kilpatrick - Annual Review of Ecology, Evolution, and …, 2023 - annualreviews.org
The coronavirus disease 2019 (COVID-19) pandemic challenged the workings of human
society, but in doing so, it advanced our understanding of the ecology and evolution of …
society, but in doing so, it advanced our understanding of the ecology and evolution of …
A phase 2 randomized trial evaluating the antiviral activity and safety of the direct-acting antiviral bemnifosbuvir in ambulatory patients with mild or moderate COVID …
M Boffito, E Dolan, K Singh, W Holmes… - Microbiology …, 2023 - Am Soc Microbiol
Bemnifosbuvir is an oral antiviral drug with a dual mechanism of action targeting viral RNA
polymerase, with in vitro activity against SARS-CoV-2. We conducted a phase 2, double …
polymerase, with in vitro activity against SARS-CoV-2. We conducted a phase 2, double …
[HTML][HTML] Clinical performance characteristics of the Swift Normalase Amplicon Panel for sensitive recovery of severe acute respiratory syndrome coronavirus 2 …
L Shrestha, MJ Lin, H Xie, MG Mills… - The Journal of Molecular …, 2022 - Elsevier
Amplicon-based sequencing methods are central in characterizing the diversity,
transmission, and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
transmission, and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
[HTML][HTML] Temporal trends of severity and outcomes of critically ill patients with COVID-19 after the emergence of variants of concern: A comparison of two waves
DHM Freitas, ELV Costa, NA Zimmermann, LSO Gois… - Plos one, 2024 - journals.plos.org
Background The emergence of SARS-CoV-2 variants led to subsequent waves of COVID-19
worldwide. In many countries, the second wave of COVID-19 was marked by record deaths …
worldwide. In many countries, the second wave of COVID-19 was marked by record deaths …