A wide range of techniques and methods are actively invented by clinicians and scientists
who are dedicated to the field of musculoskeletal tissue regeneration. Biological, chemical …

Electric fields are involved in numerous physiological processes, including directional
embryonic development and wound healing following injury. To study these processes in …

Electrical signals have been applied towards the repair of articular tissues in the laboratory
and clinical settings for over seventy years. We focus on healing of the meniscus, a tissue …

Directed cell migration and adhesion is essential to embryonic development, tissue
formation and wound healing. For decades it has been reported that electric field (EF) …

Many patients that undergo autografting suffer from donor site morbidity and risk of immune
rejection. Tissue engineering is receiving considerable attention as engineered tissues …

Endogenous electric fields (EFs) direct the migration (electrotaxis) of keratinocytes in skin
wounds, and the exogenous application of EFs may therefore improve wound healing, but …

Abstract Introduction Interleukin-1 (IL-1) and tumor necrosis factor-α (TNF-α) are up-
regulated in injured and osteoarthritic knee joints. IL-1 and TNF-α inhibit integrative …

Articular cartilage injuries are a common source of joint pain and dysfunction. As articular
cartilage is avascular, it exhibits a poor intrinsic healing capacity for self-repair. Clinically …

Objective Galvanotaxis, the migratory response of cells in response to electrical stimulation,
has been implicated in development and wound healing. The use of mesenchymal stem …

Osteoarthritis (OA) is a complex disease of the joint for which current treatments are
unsatisfactory, thus motivating development of tissue engineering (TE)-based therapies. To …