[HTML][HTML] Gap junctions

MS Nielsen, LN Axelsen, PL Sorgen… - Comprehensive …, 2012 - ncbi.nlm.nih.gov
Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …

Plasma membrane channels formed by connexins: their regulation and functions

JC Sáez, VM Berthoud, MC Branes… - Physiological …, 2003 - journals.physiology.org
Sáez, Juan C., Viviana M. Berthoud, María C. Brañes, Agustín D. Martínez, and Eric C.
Beyer. Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions …

Pannexins, a family of gap junction proteins expressed in brain

R Bruzzone, SG Hormuzdi, MT Barbe… - Proceedings of the …, 2003 - National Acad Sciences
Database search has led to the identification of a family of proteins, the pannexins, which
share some structural features with the gap junction forming proteins of invertebrates and …

Intercellular calcium signaling in astrocytes via ATP release through connexin hemichannels

CE Stout, JL Costantin, CCG Naus… - Journal of Biological …, 2002 - ASBMB
Astrocytes are capable of widespread intercellular communication via propagated increases
in intracellular Ca 2+ concentration. We have used patch clamp, dye flux, ATP assay, and …

Intercellular Ca2+ Waves: Mechanisms and Function

L Leybaert, MJ Sanderson - Physiological reviews, 2012 - journals.physiology.org
Intercellular calcium (Ca2+) waves (ICWs) represent the propagation of increases in
intracellular Ca2+ through a syncytium of cells and appear to be a fundamental mechanism …

Beyond the gap: functions of unpaired connexon channels

DA Goodenough, DL Paul - Nature reviews Molecular cell biology, 2003 - nature.com
Gap junctions consist of intercellular channels that connect the cytoplasm of adjacent cells
directly and allow the exchange of small molecules. These channels are unique in that they …

Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes

R Bruzzone, MT Barbe, NJ Jakob… - Journal of …, 2005 - Wiley Online Library
Several new findings have emphasized the role of neuron‐specific gap junction proteins
(connexins) and electrical synapses in processing sensory information and in synchronizing …

New roles for astrocytes: gap junction hemichannels have something to communicate

MVL Bennett, JE Contreras, FF Bukauskas… - Trends in …, 2003 - cell.com
Gap junctions are clusters of aqueous channels that connect the cytoplasm of adjoining
cells. Each cell contributes a hemichannel, or connexon, to each cell–cell channel. The cell …

[HTML][HTML] Electrical synapses: a dynamic signaling system that shapes the activity of neuronal networks

SG Hormuzdi, MA Filippov, G Mitropoulou… - … et Biophysica Acta (BBA …, 2004 - Elsevier
Gap junctions consist of intercellular channels dedicated to providing a direct pathway for
ionic and biochemical communication between contacting cells. After an initial burst of …

[HTML][HTML] Connexin-based gap junction hemichannels: gating mechanisms

JC Sáez, MA Retamal, D Basilio, FF Bukauskas… - … et Biophysica Acta (BBA …, 2005 - Elsevier
Connexins (Cxs) form hemichannels and gap junction channels. Each gap junction channel
is composed of two hemichannels, also termed connexons, one from each of the coupled …