Tissue mechanics, an important regulator of development and disease

NME Ayad, S Kaushik… - … Transactions of the …, 2019 - royalsocietypublishing.org
A growing body of work describes how physical forces in and around cells affect their
growth, proliferation, migration, function and differentiation into specialized types. How cells …

The peritumoral brain zone in glioblastoma: where we are and where we are going

M Giambra, A Di Cristofori, S Valtorta… - Journal of …, 2023 - Wiley Online Library
Glioblastoma (GBM) is the most aggressive and invasive primary brain tumor. Current
therapies are not curative, and patients' outcomes remain poor with an overall survival of …

[HTML][HTML] The cuproptosis-related signature associated with the tumor environment and prognosis of patients with glioma

W Wang, Z Lu, M Wang, Z Liu, B Wu, C Yang… - Frontiers in …, 2022 - frontiersin.org
Background Copper ions are essential for cellular physiology. Cuproptosis is a novel
method of copper-dependent cell death, and the cuproptosis-based signature for glioma …

A tension-mediated glycocalyx–integrin feedback loop promotes mesenchymal-like glioblastoma

JM Barnes, S Kaushik, RO Bainer, JK Sa… - Nature cell …, 2018 - nature.com
Glioblastoma multiforme (GBMs) are recurrent lethal brain tumours. Recurrent GBMs often
exhibit mesenchymal, stem-like phenotypes that could explain their resistance to therapy …

Crosstalk between GBM cells and mesenchymal stemlike cells promotes the invasiveness of GBM through the C5a/p38/ZEB1 axis

EJ Lim, S Kim, Y Oh, Y Suh, N Kaushik, JH Lee… - Neuro …, 2020 - academic.oup.com
Abstract Background Mesenchymal stemlike cells (MSLCs) have been detected in many
types of cancer including brain tumors and have received attention as stromal cells in the …

[HTML][HTML] Mesenchymal stromal-like cells in the glioma microenvironment: what are these cells?

A Clavreul, P Menei - Cancers, 2020 - mdpi.com
Simple Summary We review here what is currently known about the role of mesenchymal
stromal-like cells, which complicate our understanding of the glioma microenvironment. We …

[HTML][HTML] Tumor-associated mesenchymal stem-like cells provide extracellular signaling cue for invasiveness of glioblastoma cells

EJ Lim, Y Suh, KC Yoo, JH Lee, IG Kim, MJ Kim… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Hyaluronic acid (HA) is abundant in tumor microenvironment and closely associated with
invasiveness of glioblastoma (GBM) cells. However, the cellular mechanism underlying HA …

Glioma-associated mesenchymal stem cells

Q Kang, J Wang, S Chen, S Song, S Yu - Brain, 2024 - academic.oup.com
Recent studies revealed that glioma-associated mesenchymal stem cells play instrumental
roles in tumorigenesis and tumor progression and cannot be ignored as a cellular …

C5α secreted by tumor mesenchymal stem-like cells mediates resistance to 5-aminolevulinic acid-based photodynamic therapy against glioblastoma tumorspheres

J Park, SJ Oh, JK Shim, YB Ji, JH Moon, EH Kim… - Journal of cancer …, 2023 - Springer
Purpose Advancements in photodynamic diagnosis (PDD) and photodynamic therapy (PDT)
as a standard care in cancer therapy have been limited. This study is aimed to investigate …

[HTML][HTML] Human mesenchymal stromal cells as cellular drug-delivery vectors for glioblastoma therapy: a good deal?

A Clavreul, M Pourbaghi-Masouleh, E Roger… - Journal of Experimental …, 2017 - Springer
Background Glioblastoma (GB) is the most malignant brain tumor in adults. It is
characterized by angiogenesis and a high proliferative and invasive capacity. Standard …