Tissue mechanics, an important regulator of development and disease
A growing body of work describes how physical forces in and around cells affect their
growth, proliferation, migration, function and differentiation into specialized types. How cells …
growth, proliferation, migration, function and differentiation into specialized types. How cells …
The peritumoral brain zone in glioblastoma: where we are and where we are going
M Giambra, A Di Cristofori, S Valtorta… - Journal of …, 2023 - Wiley Online Library
Glioblastoma (GBM) is the most aggressive and invasive primary brain tumor. Current
therapies are not curative, and patients' outcomes remain poor with an overall survival of …
therapies are not curative, and patients' outcomes remain poor with an overall survival of …
[HTML][HTML] The cuproptosis-related signature associated with the tumor environment and prognosis of patients with glioma
W Wang, Z Lu, M Wang, Z Liu, B Wu, C Yang… - Frontiers in …, 2022 - frontiersin.org
Background Copper ions are essential for cellular physiology. Cuproptosis is a novel
method of copper-dependent cell death, and the cuproptosis-based signature for glioma …
method of copper-dependent cell death, and the cuproptosis-based signature for glioma …
A tension-mediated glycocalyx–integrin feedback loop promotes mesenchymal-like glioblastoma
Glioblastoma multiforme (GBMs) are recurrent lethal brain tumours. Recurrent GBMs often
exhibit mesenchymal, stem-like phenotypes that could explain their resistance to therapy …
exhibit mesenchymal, stem-like phenotypes that could explain their resistance to therapy …
Crosstalk between GBM cells and mesenchymal stemlike cells promotes the invasiveness of GBM through the C5a/p38/ZEB1 axis
EJ Lim, S Kim, Y Oh, Y Suh, N Kaushik, JH Lee… - Neuro …, 2020 - academic.oup.com
Abstract Background Mesenchymal stemlike cells (MSLCs) have been detected in many
types of cancer including brain tumors and have received attention as stromal cells in the …
types of cancer including brain tumors and have received attention as stromal cells in the …
[HTML][HTML] Mesenchymal stromal-like cells in the glioma microenvironment: what are these cells?
A Clavreul, P Menei - Cancers, 2020 - mdpi.com
Simple Summary We review here what is currently known about the role of mesenchymal
stromal-like cells, which complicate our understanding of the glioma microenvironment. We …
stromal-like cells, which complicate our understanding of the glioma microenvironment. We …
[HTML][HTML] Tumor-associated mesenchymal stem-like cells provide extracellular signaling cue for invasiveness of glioblastoma cells
EJ Lim, Y Suh, KC Yoo, JH Lee, IG Kim, MJ Kim… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Hyaluronic acid (HA) is abundant in tumor microenvironment and closely associated with
invasiveness of glioblastoma (GBM) cells. However, the cellular mechanism underlying HA …
invasiveness of glioblastoma (GBM) cells. However, the cellular mechanism underlying HA …
Glioma-associated mesenchymal stem cells
Q Kang, J Wang, S Chen, S Song, S Yu - Brain, 2024 - academic.oup.com
Recent studies revealed that glioma-associated mesenchymal stem cells play instrumental
roles in tumorigenesis and tumor progression and cannot be ignored as a cellular …
roles in tumorigenesis and tumor progression and cannot be ignored as a cellular …
C5α secreted by tumor mesenchymal stem-like cells mediates resistance to 5-aminolevulinic acid-based photodynamic therapy against glioblastoma tumorspheres
Purpose Advancements in photodynamic diagnosis (PDD) and photodynamic therapy (PDT)
as a standard care in cancer therapy have been limited. This study is aimed to investigate …
as a standard care in cancer therapy have been limited. This study is aimed to investigate …
[HTML][HTML] Human mesenchymal stromal cells as cellular drug-delivery vectors for glioblastoma therapy: a good deal?
A Clavreul, M Pourbaghi-Masouleh, E Roger… - Journal of Experimental …, 2017 - Springer
Background Glioblastoma (GB) is the most malignant brain tumor in adults. It is
characterized by angiogenesis and a high proliferative and invasive capacity. Standard …
characterized by angiogenesis and a high proliferative and invasive capacity. Standard …