The double sides of NLRP3 inflammasome activation in sepsis

C Vigneron, BF Py, G Monneret, F Venet - Clinical Science, 2023 - portlandpress.com
Sepsis is defined as a life-threatening organ dysfunction induced by a dysregulated host
immune response to infection. Immune response induced by sepsis is complex and …

Persistent NLRP3 inflammasome activation is associated with delayed immunosuppression in septic patients

R Coudereau, M Bodinier… - Journal of Leukocyte …, 2024 - academic.oup.com
Sepsis triggers a complex response marked by the simultaneous presence of
proinflammatory and immunosuppressive elements, disrupting the mechanisms intended to …

Extracellular Vesicle microRNA Biomarkers of Late Post-sepsis Survivors

T Souza-Siqueira, RB Gritte, E Weimann… - 2023 - preprints.org
Sepsis is a life-threatening condition with high hospital mortality. Elevated mortality has also
been observed in patients after hospital discharge due to post-sepsis syndrome (PSS). The …