A novel potent indazole carboxylic acid derivative blocks spermatogenesis and is contraceptive in rats after a single oral dose
JS Tash, B Attardi, SA Hild, R Chakrasali… - Biology of …, 2008 - academic.oup.com
Women have historically been the focus for development of new contraceptive methods. The
National Institutes of Health, World Health Organization, and Institute of Medicine have …
National Institutes of Health, World Health Organization, and Institute of Medicine have …
Long-term sequelae of tolnidamine on male reproduction and general body metabolism in rabbits
The long-term effects of tolnidamine on male reproduction and general body metabolism
were studied in rabbits (Oryctolagus cuniculus). The study was divided into three groups of …
were studied in rabbits (Oryctolagus cuniculus). The study was divided into three groups of …
Effects of lonidamine on testicular and epididymal proteins in the rat☆
MG Leone, E Grippa, D Guidolin, B Tita… - Reproductive …, 2000 - Elsevier
The mechanism responsible for the antispermatogenic activity of lonidamine (LND)[1-(2, 4-
dichlorobenzyl)-1H-indazole-3-carboxylic acid], a drug with low systemic toxicity and lack of …
dichlorobenzyl)-1H-indazole-3-carboxylic acid], a drug with low systemic toxicity and lack of …
Male contraception
DW Combs - Annual reports in medicinal chemistry, 1997 - Elsevier
Publisher Summary At present, voluntary sterilization by vasectomy is the most commonly
used method of male contraception despite the drawbacks of its surgical nature and …
used method of male contraception despite the drawbacks of its surgical nature and …
[PDF][PDF] Tolnidamine-Induced Changes in the Testis, Sperm Count, Fertility and Accessory Sex Glands of the Laboratory Mouse
P Singh - 2008 - sid.ir
Background: Tolnidamine-induced changes have been reported earlier on
spermatogenesis, fertility and sperm count in rat, rabbit and langur monkey. The aim of this …
spermatogenesis, fertility and sperm count in rat, rabbit and langur monkey. The aim of this …