Drug resistance remains the major cause of cancer treatment failure especially at the late
stage of the disease. However, based on their versatile chemistry, metal and metalloid …

Ferroptosis is a non‐apoptotic programmed cell death caused by the accumulation of lipid
peroxide. System Xc‐/glutathione peroxidase 4 (GPX4) axis and iron axis are two main …

Metal complexes have numerous applications in the current era, particularly in the field of
pharmaceutical chemistry and catalysis. A novel synthetic approach for the same is always a …

In this perspective, we discuss iron-complexes as drug candidates that are promising
alternatives to conventional platinum-based chemotherapies owing to their broad range of …

Non-steroidal anti-inflammatory drugs (NSAIDs) are a group of molecules which have been
found to be active against cancer cells with chemopreventive properties by targeting …

Ruthenium (II) complexes are currently considered a viable alternative to the widely used
platinum complexes as efficient anticancer agents. We herein present the synthesis and …

Diruthenacyclopentenone complexes of the general composition [Ru2Cp2 (CO) 2 {μ–η1: η3-
CH═ C (C (OH)(R)) C (═ O)}](2a–c; Cp= η5-C5H5) were synthesized in 94–96% yields …

Colorectal cancer (CRC) is one of the most common malignancies and one of the leading
causes of cancer-related death worldwide, urging the need for new and more efficient …

Two new ruthenium complexes,[Ru (η 5-Cp)(PPh 3)(2, 2'-bipy-4, 4'-R)]+ with R=-CH 2 OH
(Ru1) or dibiotin ester (Ru2) were synthesized and fully characterized. Both compounds …

Ruthenium-based complexes currently attract great attention as they hold promise to replace
platinum-based drugs as a first line cancer treatment. Whereas ruthenium arene complexes …