This white paper provides updated International Transporter Consortium (ITC)
recommendations on transporters that are important in drug development following the 3rd …

Bile acids (BAs) facilitate the absorption of dietary lipids and vitamins and have also been
identified as signaling molecules involved in regulating their own metabolism, glucose and …

Маевская Марина Викторовна—доктор медицинских наук, профессор, главный
научный сотрудник научноисследовательского отдела (НИО) инновационной терапии …

Background & Aims Bile acids (BAs) are major regulators of hepatic BA and lipid metabolism
but their mechanisms of action in non-alcoholic fatty liver disease (NAFLD) are still poorly …

Gut microbiota dysbiosis plays an important role in the progression of non-alcoholic fatty
liver disease (NAFLD), and no approved drugs are available for NAFLD treatment. In this …

The elucidation of the molecular basis of the rare disease, sitosterolemia, has revolutionized
our mechanistic understanding of how dietary sterols are excreted and how cholesterol is …

Discovered 20 years ago, fibroblast growth factor (FGF) 19, and its mouse ortholog FGF15,
were the first members of a new subfamily of FGFs able to act as hormones. During fetal life …

Diagnostics and treatment of non-alcoholic fatty liver disease: clinical guidelines of the Russian
Scientific Liver Society and the Russian gastroenterological association | Ivashkin | Russian …

В настоящем издании проанализированы и систематизированы сведения по
клиническому применению лекарственных средств, для которых гепатотропное …

Bile acids (BAs) are amphipathic molecules produced from cholesterol by the liver. Expelled
from the gallbladder upon meal ingestion, BAs serve as fat solubilizers in the intestine. BAs …