Targeted liposomal drug delivery: a nanoscience and biophysical perspective
Y Liu, KMC Bravo, J Liu - Nanoscale horizons, 2021 - pubs.rsc.org
Liposomes are a unique platform for drug delivery, and a number of liposomal formulations
have already been commercialized. Doxil is a representative example, which uses …
have already been commercialized. Doxil is a representative example, which uses …
[HTML][HTML] Liposomal drug delivery systems and anticancer drugs
Cancer is a life-threatening disease contributing to~ 3.4 million deaths worldwide. There are
various causes of cancer, such as smoking, being overweight or obese, intake of processed …
various causes of cancer, such as smoking, being overweight or obese, intake of processed …
An NIR Discrete Metallacycle constructed from Perylene Bisimide and Tetraphenylethylene Fluorophores for imaging‐guided cancer Radio‐chemotherapy
Y Ding, Z Tong, L Jin, B Ye, J Zhou, Z Sun… - Advanced …, 2022 - Wiley Online Library
To promote the clinical theranostic performances of platinum‐based anticancer drugs,
imaging capability is urgently desired, and their chemotherapeutic efficacy needs to be …
imaging capability is urgently desired, and their chemotherapeutic efficacy needs to be …
Engineering poly (ethylene glycol) nanoparticles for accelerated blood clearance inhibition and targeted drug delivery
Surface modification with poly (ethylene glycol)(PEGylation) is an effective strategy to
improve the colloidal stability of nanoparticles (NPs) and is often used to minimize cellular …
improve the colloidal stability of nanoparticles (NPs) and is often used to minimize cellular …
Rethinking CRITID procedure of brain targeting drug delivery: circulation, blood brain barrier recognition, intracellular transport, diseased cell targeting, internalization …
The past decades have witnessed great progress in nanoparticle (NP)‐based brain‐
targeting drug delivery systems, while their therapeutic potentials are yet to be fully exploited …
targeting drug delivery systems, while their therapeutic potentials are yet to be fully exploited …
[HTML][HTML] Recent advances in targeted drug delivery strategy for enhancing oncotherapy
J Li, Q Wang, G Xia, N Adilijiang, Y Li, Z Hou, Z Fan… - Pharmaceutics, 2023 - mdpi.com
Targeted drug delivery is a precise and effective strategy in oncotherapy that can accurately
deliver drugs to tumor cells or tissues to enhance their therapeutic effect and, meanwhile …
deliver drugs to tumor cells or tissues to enhance their therapeutic effect and, meanwhile …
Membrane wrapping efficiency of elastic nanoparticles during endocytosis: size and shape matter
Using coarse-grained molecular dynamics simulations, we systematically investigate the
receptor-mediated endocytosis of elastic nanoparticles (NPs) with different sizes, ranging …
receptor-mediated endocytosis of elastic nanoparticles (NPs) with different sizes, ranging …
Digesting a path forward: the utility of collagenase tumor treatment for improved drug delivery
A Dolor, FC Szoka Jr - Molecular pharmaceutics, 2018 - ACS Publications
Collagen and hyaluronan are the most abundant components of the extracellular matrix
(ECM) and their overexpression in tumors is linked to increased tumor growth and …
(ECM) and their overexpression in tumors is linked to increased tumor growth and …
Probing the Effect of Rigidity on the Cellular Uptake of Core‐Shell Nanoparticles: Stiffness Effects are Size Dependent
P Gurnani, C Sanchez‐Cano, H Xandri‐Monje… - Small, 2022 - Wiley Online Library
Nanoparticles are well established vectors for the delivery of a wide range of biomedically
relevant cargoes. Numerous studies have investigated the impact of size, shape, charge …
relevant cargoes. Numerous studies have investigated the impact of size, shape, charge …
Impacting Pancreatic Cancer Therapy in Heterotypic in Vitro Organoids and in Vivo Tumors with Specificity-Tuned, NIR-Activable Photoimmunonanoconjugates …
Despite untiring efforts to develop therapies for pancreatic ductal adenocarcinoma (PDAC),
survival statistics remain dismal, necessitating distinct approaches. Photodynamic priming …
survival statistics remain dismal, necessitating distinct approaches. Photodynamic priming …