Background Vascular dysfunction is a precursor to the atherosclerotic cascade, significantly
increasing susceptibility to cardiovascular events such as myocardial infarction or stroke …

Vascular endothelial function is essential for maintenance of health of the vessel wall and for
vasomotor control in both conduit and resistance vessels. These functions are due to the …

Dysfunction of the vascular endothelium is a hallmark of most conditions that are associated
with atherosclerosis and is therefore held to be an early feature in atherogenesis. However …

Background: Physical activity has been shown to be beneficial for the prevention and
management of hypertension. In the general population, physical activity has been shown to …

Obesity, insulin resistance, and endothelial dysfunction closely coexist throughout the
natural history of type 2 diabetes. They all can be identified not only in people with type 2 …

The effects of inactivity and exercise training on established and novel cardiovascular risk
factors are relatively modest and do not account for the impact of inactivity and exercise on …

Endothelial dysfunction comprises a number of functional alterations in the vascular
endothelium that are associated with diabetes and cardiovascular disease, including …

In the past two decades, normal endothelial function has been identified as integral to
vascular health. The endothelium produces numerous vasodilator and vasoconstrictor …

Obesity is a metabolic disorder of increasing prevalence worldwide and a risk factor for the
development of insulin resistance (IR), metabolic syndrome and type 2 diabetes. Obesity is …

Obesity is a chronic disease, whose incidence is alarmingly growing, affecting not only
adults but also children and adolescents. It is associated with severe metabolic …