Atherothrombosis is no longer considered solely a disorder of lipoprotein accumulation in
the arterial wall. Rather, the initiation and progression of atherosclerotic lesions is currently …

Large DNA viruses defend against hostile assault executed by the host immune system by
producing an array of gene products that systematically sabotage key components of the …

Objectives. We examined the relative contributions of inflammation and arterial injury to
neointimal formation in a porcine coronary overstretch restenosis model. Background …

SARS‐CoV‐2 acute respiratory distress syndrome (ARDS) induces uncontrolled lung
inflammation and coagulopathy with high mortality. Anti‐viral drugs and monoclonal …

The underlying role of inflammation in atherosclerosis has been characterized. However,
current treatment of coronary artery disease (CAD) predominantly consists of targeted …

Myxomatosis in European rabbits is a severely debilitating disease characterized by
profound systemic cellular immunosuppression and a high rate of mortality. The causative …

Extracellular proteolysis plays a key role in many pathophysiologic processes including
cancer, inflammatory diseases, and cardiovascular conditions such as atherosclerosis and …

Successful transmission by viruses in the face of vigorous innate and acquired host
immunity requires the ability to evade, obstruct, or subvert critical elements that mediate host …

Background Plasminogen-deficient mice display impaired vascular wound healing and
reduced arterial neointima formation after arterial injury, suggesting that inhibition of plasmin …

Variola virus, the causative agent of smallpox, is a member of the poxvirus family and one of
the most virulent human pathogens known. Although smallpox was eradicated almost 30 …