The influence of gastrointestinal biomolecules on solid-state transformations in pharmaceutical particulates
Adsorption of gut relevant biomolecules onto particles after oral administration of solid oral
dosage forms is expected to form a “gastrointestinal corona”, which could influence solution …
dosage forms is expected to form a “gastrointestinal corona”, which could influence solution …
Characterization of Variably Substituted Hydroxyapatites Using Low-Frequency Raman Spectroscopy
J Kirkham, TM Korter, K Be̅rziņš… - Crystal Growth & …, 2023 - ACS Publications
Low-frequency Raman spectroscopy was used to characterize variably substituted
hydroxyapatites with Sr2+, F–, and CO32–as the substituting species in the crystalline and …
hydroxyapatites with Sr2+, F–, and CO32–as the substituting species in the crystalline and …
In Situ Monitoring of Drug Precipitation from Digesting Lipid Formulations Using Low-Frequency Raman Scattering Spectroscopy
Low-frequency Raman spectroscopy (LFRS) is a valuable tool to detect the solid state of
amorphous and crystalline drugs in solid dosage forms and the transformation of drugs …
amorphous and crystalline drugs in solid dosage forms and the transformation of drugs …
Monitoring the Dissolution Behavior of Novel Pharmaceutical Cocrystals Consisting of Antimalarial Drug Artemisinin with Probe-Type Low-Frequency Raman …
T Kudo, S Miura, K Takatori… - Applied …, 2024 - journals.sagepub.com
Artemisinin (ART) is a most promising antimalarial agent. However, its low aqueous
solubility limits its oral absorption, resulting in low bioavailability. In this study, we have …
solubility limits its oral absorption, resulting in low bioavailability. In this study, we have …
[PDF][PDF] Utility of Low Frequency (LF) Raman Mapping: Dissolution of Acetaminophen (ACE) Spray Dried Dispersions (SDD)
N Setiawan, A Smith, DE Bugay - 2023 - tricliniclabs.com
This application note outlines the evaluation of post-dissolution ACE SDD. The results
indicated that in all of the cases studied, ACE remained amorphous upon dissolution if it was …
indicated that in all of the cases studied, ACE remained amorphous upon dissolution if it was …