To adapt to and anticipate rhythmic changes in the environment such as daily light–dark and
temperature cycles, internal timekeeping mechanisms called biological clocks evolved in a …

All living organisms experience daily environmental cycles and have consequently evolved
to synchronize and adapt to this changing environment. Biological processes such as …

The aging eye experiences physiological changes that include decreased visual function
and increased risk of retinal degeneration. Although there are transcriptomic signatures in …

Circadian clocks are evolved to adapt to the daily environmental changes under different
conditions. The ability to maintain circadian clock functions in response to various stresses …

Circadian clock and chromatin-remodeling complexes are tightly intertwined systems that
regulate rhythmic gene expression. The circadian clock promotes rhythmic expression …

Simple Summary Clock proteins and their collaborating transcription factors often act as
distal enhancers to regulate the rhythmic transcription of gene promoters. Those …

Insects, like most organisms, have an internal circadian clock that oscillates with a daily
rhythmicity, and a timing mechanism (photoperiodic clock) that mediates seasonal events …

Circadian rhythms reflect daily variations in our physiological state such as sleep, body
temperature and hormonal secretion. At the cellular level, they are driven by a molecular …

Aging is characterized by changes in transcriptional outputs that correlate with physiological
changes observed as we age, including decreased function, and increased cell death …

Aging is characterized by changes in transcriptional outputs that correlate with physiological
changes observed as we age, including decreased function, and increased cell death …