In humans and experimental animals. infections or inflammatory stimuli cause changes in
the activities and expression levels of various forms of cytochrome P450 (P450) in the liver …

Nitric oxide (NO), a signaling molecule, regulates biological functions in multiple
organs/tissues, including the epidermis, where it impacts permeability barrier homeostasis …

Injection of carrageenan 1%(50 μl) in the mouse paw causes a biphasic response: an early
inflammatory response that lasts 6 h and a second late response that peaks at 72 h …

1 The role of nitric oxide (NO) derived from constitutive and inducible nitric oxide synthase
(cNOS and iNOS) and its relationship to oxygen‐derived free radicals and prostaglandins …

Two ethanolic propolis extracts (EPE) with and without the caffeic acid phenethyl ester
(CAPE), CAPE and galangin (major components of propolis) were investigated for anti …

Many human diseases are associated with the overproduction of oxygen free radicals that
inflict cell damage. A manganese (II) complex with a bis (cyclohexylpyridine)-substituted …

The local production of proinflammatory cytokines mediates the host response to
inflammation, infection, and injury, whereas an overexpression of these mediators can injure …

IL-18 expression and functional activity has been identified in several autoimmune and
infectious diseases. To clarify the potential role of IL-18 during early innate immune …

Abstract IL-12 and IL-10, respectively, stimulate Th1 and Th2 immune responses. The
development of some allergic reactions, infections, and tumors are associated with …

Publisher Summary This chapter reviews the role of cytokines in the pathogenesis of sepsis.
The various models for sepsis are also discussed, including the human models and animal …