An update of epigenetic drugs for the treatment of cancers and brain diseases: a comprehensive review
Z Sahafnejad, S Ramazi, A Allahverdi - Genes, 2023 - mdpi.com
Epigenetics has long been recognized as a significant field in biology and is defined as the
investigation of any alteration in gene expression patterns that is not attributed to changes in …
investigation of any alteration in gene expression patterns that is not attributed to changes in …
[HTML][HTML] Upstream and downstream regulators of Klotho expression in chronic kidney disease
SS Li, M Sheng, ZY Sun, Y Liang, LX Yu, QF Liu - Metabolism, 2023 - Elsevier
Klotho is a critical protein that protects the kidney. Klotho is severely downregulated in
chronic kidney disease (CKD), and its deficiency is implicated in the pathogenesis and …
chronic kidney disease (CKD), and its deficiency is implicated in the pathogenesis and …
MLCPP 2.0: an updated cell-penetrating peptides and their uptake efficiency predictor
B Manavalan, MC Patra - Journal of Molecular Biology, 2022 - Elsevier
Cell-penetrating peptides (CPPs) translocate into the cell as various biologically active
conjugates and possess numerous biomedical applications. Several machine learning …
conjugates and possess numerous biomedical applications. Several machine learning …
Crossing epigenetic frontiers: the intersection of novel histone modifications and diseases
W Yao, X Hu, X Wang - Signal Transduction and Targeted Therapy, 2024 - nature.com
Histone post-translational modifications (HPTMs), as one of the core mechanisms of
epigenetic regulation, are garnering increasing attention due to their close association with …
epigenetic regulation, are garnering increasing attention due to their close association with …
Epigenetic regulation in lung cancer
S Ramazi, M Dadzadi, Z Sahafnejad, A Allahverdi - MedComm, 2023 - Wiley Online Library
Lung cancer is indeed a major cause of cancer‐related deaths worldwide. The development
of tumors involves a complex interplay of genetic, epigenetic, and environmental factors …
of tumors involves a complex interplay of genetic, epigenetic, and environmental factors …
Introduction to epigenetics
Epigenetics is the study of inherited variations in gene expression that do not involve
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …
[HTML][HTML] Epigenetic Modifications of Hormonal Signaling Pathways in Plant Drought Response and Tolerance for Sustainable Food Security
Drought significantly challenges global food security, necessitating a comprehensive
understanding of plant molecular responses for effective mitigation strategies. Epigenetic …
understanding of plant molecular responses for effective mitigation strategies. Epigenetic …
Epigenetics and plant hormone dynamics: a functional and methodological perspective
J Rudolf, L Tomovicova, K Panzarova… - Journal of …, 2024 - academic.oup.com
Plant hormones, pivotal regulators of plant growth, development, and response to
environmental cues, have recently emerged as central modulators of epigenetic processes …
environmental cues, have recently emerged as central modulators of epigenetic processes …
Mechanism and therapeutic opportunities of histone modifications in chronic liver disease
Q Cai, C Gan, C Tang, H Wu, J Gao - Frontiers in Pharmacology, 2021 - frontiersin.org
Chronic liver disease (CLD) represents a global health problem, accounting for the heavy
burden of disability and increased health care utilization. Epigenome alterations play an …
burden of disability and increased health care utilization. Epigenome alterations play an …
DNA Methylation in the Fields of Prenatal Diagnosis and Early Detection of Cancers
The central objective of the metamorphosis of discovery science into biomedical
applications is to serve the purpose of patients and curtail the global disease burden. The …
applications is to serve the purpose of patients and curtail the global disease burden. The …