As crucial antigen presenting cells, dendritic cells (DCs) play a vital role in tumor
immunotherapy. Taking into account the many recent advances in DC biology, we discuss …

Pemphigus is a group of IgG-mediated autoimmune diseases of stratified squamous
epithelia, such as the skin and oral mucosa, in which acantholysis (the loss of cell adhesion) …

Inflammatory processes and microglia activation accompany most of the pathophysiological
diseases in the central nervous system. It is proven that glial pathology precedes and even …

To combat the HIV epidemic and emerging threats such as SARS-CoV-2, immunization
strategies are needed that elicit protection at mucosal portals of pathogen entry …

Antibody-based proteins have become an important class of biologic therapeutics, due in
large part to the stability, specificity, and adaptability of the antibody framework. Indeed …

The cellular uptake, intracellular processing, and presentation of foreign antigen are crucial
processes for eliciting an effective adaptive host response to the majority of pathogens. The …

The neonatal Fc receptor (FcRn) was first found to be responsible for transporting antibodies
of the immunoglobulin G (IgG) class from the mother to the fetus or neonate as well as for …

The humoral immune response provides specific, long-lived protection against invading
pathogens, via immunoglobulin production and other memory functions. IgG, the most …

At birth, neonates are particularly vulnerable to infection and transplacental transfer of
immunoglobulin G (IgG) from mother to fetus provides crucial protection in the first weeks of …

The neonatal Fc receptor (FcRn) is a major histocompatibility complex class I type molecule
that binds to, transports, and recycles immunoglobulin G (IgG) and albumin, thereby …