Septins are an integral component of the cytoskeleton, assembling into higher-order
oligomers and filamentous polymers that associate with actin filaments, microtubules and …

Septins belong to a family of proteins that is highly conserved in eukaryotes and is
increasingly recognized as a novel component of the cytoskeleton. All septins are GTP …

Asymmetric cell division, which includes cell polarization and cytokinesis, is essential for
generating cell diversity during development. The budding yeast Saccharomyces cerevisiae …

Septins are GTP-binding proteins that form filaments and higher-order structures on the cell
cortex of eukaryotic cells and associate with actin and microtubule cytoskeletal networks …

Septins perform diverse functions through the formation of filaments and higher-order
structures. However, the exact architecture of septin structures remains unclear. In the …

How adhesive contacts with neighbors may affect epithelial cell cytokinesis is unknown. We
report that in Drosophila, septins are specifically required for planar (but not orthogonal) …

The septin family of proteins has fascinated cell biologists for decades due to the elaborate
architecture they adopt in different eukaryotic cells. Whether they exist as rings, collars, or …

Septins are a unique family of GTPases, which were discovered 50 years ago as essential
genes for the asymmetric cell shape and division of budding yeast. Septins assemble into …

Cell division is a fundamental but complex process that gives rise to two daughter cells. It
includes an ordered set of events, altogether called “the cell cycle”, that culminate with …

Cytokinesis is essential for cell proliferation in all domains of life. Because the core
components and mechanisms of cytokinesis are conserved from fungi to humans, the …