Metabolomics generates a profile of small molecules that are derived from cellular
metabolism and can directly reflect the outcome of complex networks of biochemical …

Metabolite profiling is critical in many aspects of the life sciences, particularly natural product
research. Obtaining precise information on the chemical composition of complex natural …

Objectives Decreased gut microbial gene richness (MGR) and compositional changes are
associated with adverse metabolism in overweight or moderate obesity, but lack …

Background & Aims Acute-on-chronic liver failure (ACLF), which develops in patients with
cirrhosis, is characterized by intense systemic inflammation and organ failure (s). Because …

Metabolomics deals with the large-scale analysis of metabolites, belonging to numerous
compound classes and showing an extremely high chemical diversity and complexity …

Metabolomics refers to the large-scale detection, quantification, and analysis of small
molecules (metabolites) in biological media. Although metabolomics, alone or combined …

Profiling of body fluids is crucial for monitoring and discovering metabolic markers of health
and disease and for providing insights into human physiology. Since human urine and …

Untargeted metabolomics is now widely recognized as a useful tool for exploring metabolic
changes taking place in biological systems under different conditions. By its nature, this is a …

Physical exercise can produce changes in the microbiota, conferring health benefits through
mechanisms that are not fully understood. We sought to determine the changes driven by …

Typical mass spectrometry (MS) based untargeted metabolomics protocols are tedious as
well as time-and sample-consuming. In particular, they often rely on “full-scan-only” …