Recent developments in molecular biology and genomics have revolutionized biology and
medicine mainly in the developed world. The application of next generation sequencing …

Background Malaria infection during pregnancy endangers the pregnant woman, fetus, and
newborn child. Thus, the use of an insecticide-treated net (ITN) is one of the most frequently …

Artemisinin and its derivatives (ARTs) are frontline antimalarial drugs. However, ART
monotherapy is associated with a high frequency of recrudescent infection, resulting in …

Background. Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) is a
blood-stage parasite protein essential for host erythrocyte invasion. PfRH5-specific …

Controlled human malaria infection (CHMI) by mosquito bite has been used to assess anti-
malaria interventions in> 1,500 volunteers since development of methods for infecting …

Immunity that controls parasitemia and inflammation during Plasmodium falciparum (Pf)
malaria can be acquired with repeated infections. A limited understanding of this complex …

The development of resistance to antimalarials is a major challenge for global malaria
control. Artemisinin-based combination therapies, the newest class of antimalarials, are …

Routine therapeutic efficacy monitoring to measure the response to antimalarial treatment is
a cornerstone of malaria control. To correctly measure drug efficacy, therapeutic efficacy …

Background Malaria-associated anaemia, arising from symptomatic, asymptomatic and
submicroscopic infections, is a significant cause of morbidity worldwide. Induced blood …

Background The efficacy of artemether-lumefantrine (AL) for treatment of uncomplicated
Plasmodium falciparum malaria in south-western Ethiopia is poorly documented. Regular …