We review the current status of proton FLASH experimental systems, including preclinical
physical and biological results. Technological limitations on preclinical investigation of …

Magnetic nanoparticle (MNP)-mediated hyperthermia (MH) coupled with radiation therapy
(RT) is a novel approach that has the potential to overcome various practical difficulties …

Many radiotherapy research centers have recently installed novel research platforms
enabling the investigation of the radiation response of tumors and normal tissues in small …

Background The purpose of this study was to introduce an experimental radiobiological
setup used for in vivo irradiation of a mouse leg target in multiple positions along a proton …

For image-guided small animal irradiations, the whole workflow of imaging, organ
contouring, irradiation planning, and delivery is typically performed in a single session …

This Roadmap paper covers the field of precision preclinical x-ray radiation studies in
animal models. It is mostly focused on models for cancer and normal tissue response to …

Extraordinary normal tissue response to highly spatially fractionated X-ray beams has been
explored for over 25 years. More recently, alternative radiation sources have been …

Background: Precision small animal radiotherapy research is a young emerging field aiming
to provide new experimental insights into tumor and normal tissue models in different …

Radiographic imaging with x-rays and protons is an omnipresent tool in basic research and
applications in industry, material science and medical diagnostics. The information …

Background and purpose Proton radiotherapy offers the potential to reduce normal tissue
toxicity. However, clinical safety margins, range uncertainties, and varying relative biological …