The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions
BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
Chemically modified and conjugated antimicrobial peptides against superbugs
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
Peptide design and self-assembly into targeted nanostructure and functional materials
Peptides have been extensively utilized to construct nanomaterials that display targeted
structure through hierarchical assembly. The self-assembly of both rationally designed …
structure through hierarchical assembly. The self-assembly of both rationally designed …
Biocompatible synthetic polymers for tissue engineering purposes
Z Terzopoulou, A Zamboulis, I Koumentakou… - …, 2022 - ACS Publications
Synthetic polymers have been an integral part of modern society since the early 1960s.
Besides their most well-known applications to the public, such as packaging, construction …
Besides their most well-known applications to the public, such as packaging, construction …
Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation
The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …
Charge reversal nano-systems for tumor therapy
P Zhang, D Chen, L Li, K Sun - Journal of Nanobiotechnology, 2022 - Springer
Surface charge of biological and medical nanocarriers has been demonstrated to play an
important role in cellular uptake. Owing to the unique physicochemical properties, charge …
important role in cellular uptake. Owing to the unique physicochemical properties, charge …
pH-Sensitive nanogels for drug delivery in cancer therapy
Z Li, J Huang, J Wu - Biomaterials Science, 2021 - pubs.rsc.org
As a commonly used treatment method for cancer, chemotherapy is greatly limited by the
side effects of chemotherapy drugs and the multiple drug resistance that develops …
side effects of chemotherapy drugs and the multiple drug resistance that develops …
Intelligent poly (l-histidine)-based nanovehicles for controlled drug delivery
Stimuli-responsive drug delivery systems based on polymeric nanovehicles are among the
most promising treatment regimens for malignant cancers. Such intelligent systems that …
most promising treatment regimens for malignant cancers. Such intelligent systems that …
Recent Advances in Poly(α-L-glutamic acid)-Based Nanomaterials for Drug Delivery
Poly (α-L-glutamic acid)(PGA) is a class of synthetic polypeptides composed of the
monomeric unit α-L-glutamic acid. Owing to their biocompatibility, biodegradability, and non …
monomeric unit α-L-glutamic acid. Owing to their biocompatibility, biodegradability, and non …
Host defense peptide mimicking antimicrobial amino acid polymers and beyond: design, synthesis and biomedical applications
Y Wu, K Chen, J Wang, M Chen, Y Chen, Y She… - Progress in Polymer …, 2023 - Elsevier
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …
countless human lives, however, is seriously challenged by the quick emergence of …