[HTML][HTML] The applied implications of epigenetics in anxiety, affective and stress-related disorders-A review and synthesis on psychosocial stress, psychotherapy and …
MA Schiele, MG Gottschalk, K Domschke - Clinical psychology review, 2020 - Elsevier
Mental disorders are highly complex and multifactorial in origin, comprising an elaborate
interplay of genetic and environmental factors. Epigenetic mechanisms such as DNA …
interplay of genetic and environmental factors. Epigenetic mechanisms such as DNA …
Systemic inflammation mediates age-related cognitive deficits
The association between systemic inflammation and cognitive deficits is well-documented.
Further, previous studies have shown that systemic inflammation levels increase with age …
Further, previous studies have shown that systemic inflammation levels increase with age …
Pathophysiology and individualized treatment of hypothalamic obesity following craniopharyngioma and other suprasellar tumors: a systematic review
L van Iersel, KE Brokke, RAH Adan… - Endocrine …, 2019 - academic.oup.com
The development of hypothalamic obesity (HO) following craniopharyngioma (CP) and other
suprasellar tumors leads to reduced patient quality of life. No treatment algorithms are …
suprasellar tumors leads to reduced patient quality of life. No treatment algorithms are …
Genetic, epigenetic, and environmental factors controlling oxytocin receptor gene expression
Background The neuropeptide oxytocin regulates mammalian social behavior. Disruptions
in oxytocin signaling are a feature of many psychopathologies. One commonly studied …
in oxytocin signaling are a feature of many psychopathologies. One commonly studied …
[HTML][HTML] Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies
The human oxytocin (OXT) system is implicated in the regulation of complex social
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …
Decreased oxytocin plasma levels and oxytocin receptor expression associated with aggressive behavior in aggressive-impulsive disorders
M Diaz-Marsá, JM López-Villatoro… - Journal of Psychiatric …, 2024 - Elsevier
Introduction This study aims to enhance the understanding of the association between the
phenotypic and endophenotypic characteristics of impulsive-aggressive disorders, through …
phenotypic and endophenotypic characteristics of impulsive-aggressive disorders, through …
Possible oxytocin-related biomarkers in anxiety and mood disorders
S Yoon, YK Kim - Progress in Neuro-Psychopharmacology and …, 2022 - Elsevier
Anxiety and mood disorders are prevalent, disabling, and frequently difficult to treat. Such
disorders are often comorbid and share similar characteristics. For more accurate diagnosis …
disorders are often comorbid and share similar characteristics. For more accurate diagnosis …
Abnormal neuronal morphology and altered synaptic proteins are restored by oxytocin in autism-related SHANK3 deficient model
A Reichova, Z Bacova, S Bukatova… - Molecular and Cellular …, 2020 - Elsevier
Oxytocin has been suggested as a potential therapeutic agent in autism and other
neuropsychiatric conditions. Although, the link between the deficit in “SH3 domain and …
neuropsychiatric conditions. Although, the link between the deficit in “SH3 domain and …
Oxytocin receptor gene (OXTR) DNA methylation is associated with autism and related social traits–A systematic review
M Moerkerke, ML Bonte, N Daniels, V Chubar… - Research in Autism …, 2021 - Elsevier
There is emerging evidence implicating oxytocin receptor gene (OXTR) DNA methylation
(DNAm) in social behaviour. This review investigated its association with autism spectrum …
(DNAm) in social behaviour. This review investigated its association with autism spectrum …
An epigenetic rheostat of experience: DNA methylation of OXTR as a mechanism of early life allostasis
Oxytocin is a neuropeptide hormone which is involved in regulation of social behavior,
stress response, muscle contraction, and metabolism. Oxytocin signaling is dependent on its …
stress response, muscle contraction, and metabolism. Oxytocin signaling is dependent on its …