Megacities are intricate systems that struggle with difficulties including overcrowding, subpar
urban design and planning, inadequate mobility and public transportation, subpar …

Multiscale and multiphysics applications are now commonplace, and many researchers
focus on combining existing models to construct new multiscale models. This concise review …

We argue that, despite the fact that the field of multiscale modelling and simulation has
enjoyed significant success within the past decade, it still holds many open questions that …

We expect that multiscale simulations will be one of the main high performance computing
workloads in the exascale era. We propose multiscale computing patterns as a generic …

Abstract We present the Multiscale Coupling Library and Environment: MUSCLE 2. This
multiscale component-based execution environment has a simple to use Java, C++, C …

Inherently complex problems from many scientific disciplines require a multiscale modeling
approach. Yet its practical contents remain unclear and inconsistent. Moreover, multiscale …

In the last few decades, multiscale modelling has emerged as one of the dominant
modelling paradigms in many areas of science and engineering. Its rise to dominance is …

Neointimal hyperplasia, a process of smooth muscle cell re-growth, is the result of a natural
wound healing response of the injured artery after stent deployment. Excessive neointimal …

Recent multiscale applications require more and more often the coupling of many sub-
models, usually originating form different fields of science. Therefore, it is increasingly …

In this paper, we report on the experimental results of running a large, tightly coupled,
distributed multiscale computation over a hybrid High Performance Computing (HPC) …