The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”

GH Meftahi, Z Jangravi, H Sahraei, Z Bahari - Inflammation Research, 2020 - Springer
Abstract Purpose Novel Coronavirus disease 2019 (COVID-19), is an acute respiratory
distress syndrome (ARDS), which is emerged in Wuhan, and recently become worldwide …

Cell death in liver diseases: a review

L Shojaie, A Iorga, L Dara - International journal of molecular sciences, 2020 - mdpi.com
Regulated cell death (RCD) is pivotal in directing the severity and outcome of liver injury.
Hepatocyte cell death is a critical event in the progression of liver disease due to resultant …

Gut microbiota reinforce host antioxidant capacity via the generation of reactive sulfur species

J Uchiyama, M Akiyama, K Hase, Y Kumagai, YG Kim - Cell Reports, 2022 - cell.com
Gut microbiota act beyond the gastrointestinal tract to regulate the physiology of the host.
However, their contribution to the antioxidant capacity of the host remains largely …

The role of inflammation in autoimmune disease: a therapeutic target

Y Xiang, M Zhang, D Jiang, Q Su, J Shi - Frontiers in Immunology, 2023 - frontiersin.org
Autoimmune diseases (AIDs) are immune disorders whose incidence and prevalence are
increasing year by year. AIDs are produced by the immune system's misidentification of self …

Interleukin-1 family cytokines: keystones in liver inflammatory diseases

L Barbier, M Ferhat, E Salamé, A Robin… - Frontiers in …, 2019 - frontiersin.org
The pyrogenic property being the first activity described, members of the interleukin-1
superfamily (IL-1α, IL-1β, IL-18, and the newest members: IL-33, IL-36, IL-37, and IL-38) are …

NOD-like receptors in autoimmune diseases

L Chen, S Cao, Z Lin, S He, J Zuo - Acta Pharmacologica Sinica, 2021 - nature.com
Autoimmune diseases are chronic immune diseases characterized by dysregulation of
immune system, which ultimately results in a disruption in self-antigen tolerance. Cumulative …

[HTML][HTML] Pyroptosis in liver disease: new insights into disease mechanisms

J Wu, S Lin, B Wan, B Velani, Y Zhu - Aging and disease, 2019 - ncbi.nlm.nih.gov
There has been increasing interest in pyroptosis as a novel form of pro-inflammatory
programmed cell death. The mechanism of pyroptosis is significantly different from other …

Nod-like receptors: critical intracellular sensors for host protection and cell death in microbial and parasitic infections

AO Babamale, ST Chen - International journal of molecular sciences, 2021 - mdpi.com
Cell death is an essential immunological apparatus of host defense, but dysregulation of
mutually inclusive cell deaths poses severe threats during microbial and parasitic infections …

The gut microbiota: a novel player in autoimmune hepatitis

Z Cheng, L Yang, H Chu - Frontiers in cellular and infection …, 2022 - frontiersin.org
Autoimmune hepatitis (AIH) is a chronic immune-mediated liver disease distributed globally
in all ethnicities with increasing prevalence. If left untreated, the disease will lead to …

The role of the NLRP3 inflammasome and programmed cell death in acute liver injury

C Yu, P Chen, L Miao, G Di - International Journal of Molecular Sciences, 2023 - mdpi.com
Acute liver injury (ALI) is a globally important public health issue that, when severe, rapidly
progresses to acute liver failure, seriously compromising the life safety of patients. The …