Spatially and temporally restricted expression of the Hox genes along the main and
appendicular axes is essential for correct patterning of vertebrate embryos. In this overview …

Major advances have been made in understanding the evolution of transcriptional
regulation using microevolutionary and macroevolutionary experimental approaches. The …

In Drosophila, a hierarchy of maternal, gap, pair-rule, and segment polarity gene interactions
regulates virtually simultaneous blastoderm segmentation. For the last decade, studies have …

The insect body plan is very well conserved, yet the developmental mechanisms of
segmentation are surprisingly varied. Less evolutionarily derived insects undergo short …

Leg development in Drosophila has been studied in much detail. However, Drosophila limbs
form in the larva as imaginal discs and not during embryogenesis as in most other …

Over the past two to three decades, developmental biology has demonstrated that all
multicellular organisms in the animal kingdom share many of the same molecular building …

We isolated the homologue of the Drosophila gene dachshund (dac) from the beetle
Tribolium castaneum. Tc'dac is expressed in all appendages except urogomphi and …

Although the molecular mechanisms directing anteroposterior patterning of the Drosophila
embryo (long-germband mode) are well understood, how these mechanisms were evolved …

During the anterior− posterior fate specification of insects, anterior fates arise in a
nonelongating tissue (called the “blastoderm”), and posterior fates arise in an elongating …

The recent establishment of broadly applicable genetic transformation systems will allow the
analysis of gene function in diverse insect species. This will increase our understanding of …