3D bioprinted cancer models: from basic biology to drug development
Effort invested in the development of new drugs often fails to be translated into meaningful
clinical benefits for patients with cancer. The development of more effective anticancer …
clinical benefits for patients with cancer. The development of more effective anticancer …
Harnessing 3D in vitro systems to model immune responses to solid tumours: a step towards improving and creating personalized immunotherapies
In vitro 3D models are advanced biological tools that have been established to overcome
the shortcomings of oversimplified 2D cultures and mouse models. Various in vitro 3D …
the shortcomings of oversimplified 2D cultures and mouse models. Various in vitro 3D …
Programming 3D curved mesosurfaces using microlattice designs
Cellular microstructures form naturally in many living organisms (eg, flowers and leaves) to
provide vital functions in synthesis, transport of nutrients, and regulation of growth. Although …
provide vital functions in synthesis, transport of nutrients, and regulation of growth. Although …
[HTML][HTML] Converging bioprinting and organoids to better recapitulate the tumor microenvironment
X Wang, Y Luo, Y Ma, P Wang, R Yao - Trends in biotechnology, 2024 - cell.com
Bioprinting shows excellent potential for preclinical tumor modeling, with significant
advantages over 2D cell cultures in replicating the tumor microenvironment (TME). Recently …
advantages over 2D cell cultures in replicating the tumor microenvironment (TME). Recently …
Organoids: The current status and biomedical applications
S Yang, H Hu, H Kung, R Zou, Y Dai, Y Hu… - MedComm, 2023 - Wiley Online Library
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …
NIR-II bioimaging of small molecule fluorophores: From basic research to clinical applications
C Li, X Guan, X Zhang, D Zhou, S Son, Y Xu… - Biosensors and …, 2022 - Elsevier
Due to the low autofluorescence and deep-photo penetration, the second near-infrared
region fluorescence imaging technology (NIR-II, 1000–2000 nm) has been widely utilized in …
region fluorescence imaging technology (NIR-II, 1000–2000 nm) has been widely utilized in …
Understanding and targeting resistance mechanisms in cancer
Resistance to cancer therapies has been a commonly observed phenomenon in clinical
practice, which is one of the major causes of treatment failure and poor patient survival. The …
practice, which is one of the major causes of treatment failure and poor patient survival. The …
Micro-engineering and nano-engineering approaches to investigate tumour ecosystems
The interactions among tumour cells, the tumour microenvironment (TME) and non-tumour
tissues are of interest to many cancer researchers. Micro-engineering approaches and …
tissues are of interest to many cancer researchers. Micro-engineering approaches and …
Advances in 3D bioprinting for cancer biology and precision medicine: From matrix design to application
MS Jung, S Ghamrawi, EY Du… - Advanced …, 2022 - Wiley Online Library
The tumor microenvironment is highly complex owing to its heterogeneous composition and
dynamic nature. This makes tumors difficult to replicate using traditional 2D cell culture …
dynamic nature. This makes tumors difficult to replicate using traditional 2D cell culture …
Embedded bioprinting of breast tumor cells and organoids using low‐concentration collagen‐based bioinks
Bioinks for 3D bioprinting of tumor models should not only meet printability requirements but
also accurately maintain and support phenotypes of tumor surrounding cells to recapitulate …
also accurately maintain and support phenotypes of tumor surrounding cells to recapitulate …