Trans-Acting Small RNAs and Their Effects on Gene Expression in Escherichia coli and Salmonella enterica

J Hör, G Matera, J Vogel, S Gottesman, G Storz - EcoSal Plus, 2020 - Am Soc Microbiol
The last few decades have led to an explosion in our understanding of the major roles that
small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in …

Regulation of mRNA stability during bacterial stress responses

DA Vargas-Blanco, SS Shell - Frontiers in microbiology, 2020 - frontiersin.org
Bacteria have a remarkable ability to sense environmental changes, swiftly regulating their
transcriptional and posttranscriptional machinery as a response. Under conditions that …

Regulatory roles of Escherichia coli 5' UTR and ORF-internal RNAs detected by 3' end mapping

PP Adams, G Baniulyte, C Esnault, K Chegireddy… - Elife, 2021 - elifesciences.org
Many bacterial genes are regulated by RNA elements in their 5´ untranslated regions
(UTRs). However, the full complement of these elements is not known even in the model …

[HTML][HTML] Global RNA interactome of Salmonella discovers a 5′ UTR sponge for the MicF small RNA that connects membrane permeability to transport capacity

G Matera, Y Altuvia, M Gerovac, Y El Mouali, H Margalit… - Molecular cell, 2022 - cell.com
The envelope of Gram-negative bacteria is a vital barrier that must balance protection and
nutrient uptake. Small RNAs are crucial regulators of the envelope composition and function …

Prevalence of small base-pairing RNAs derived from diverse genomic loci

PP Adams, G Storz - Biochimica Et Biophysica Acta (BBA)-Gene …, 2020 - Elsevier
Small RNAs (sRNAs) that act by base-pairing have been shown to play important roles in
fine-tuning the levels and translation of their target transcripts across a variety of model and …

Selective 8-oxo-rG stalling occurs in the catalytic core of polynucleotide phosphorylase (PNPase) during degradation

LG Miller, W Kim, S Schowe, K Taylor, R Han… - Proceedings of the …, 2024 - pnas.org
RNA oxidation, predominantly through the accumulation of 8-oxo-7, 8-dihydroguanosine (8-
oxo-rG), represents an important biomarker for cellular oxidative stress. Polynucleotide …

Grad‐seq in a Gram‐positive bacterium reveals exonucleolytic sRNA activation in competence control

J Hör, G Garriss, S Di Giorgio, LM Hack… - The EMBO …, 2020 - embopress.org
RNA–protein interactions are the crucial basis for many steps of bacterial gene expression,
including post‐transcriptional control by small regulatory RNA s (sRNA s). In stark contrast to …

Methodologies for bacterial ribonuclease characterization using RNA-seq

L Broglia, A Le Rhun… - FEMS microbiology …, 2023 - academic.oup.com
Bacteria adjust gene expression at the post-transcriptional level through an intricate network
of small regulatory RNAs and RNA-binding proteins, including ribonucleases (RNases) …

A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation

T Dendooven, D Sinha, A Roeselová, TA Cameron… - Molecular Cell, 2021 - cell.com
Polynucleotide phosphorylase (PNPase) is an ancient exoribonuclease conserved in the
course of evolution and is found in species as diverse as bacteria and humans …

Comparison of transcriptional profiles of Treponema pallidum during experimental infection of rabbits and in vitro culture: Highly similar, yet different

BD De Lay, TA Cameron, NR De Lay, SJ Norris… - PLoS …, 2021 - journals.plos.org
Treponema pallidum ssp. pallidum, the causative agent of syphilis, can now be cultured
continuously in vitro utilizing a tissue culture system, and the multiplication rates are similar …