Acute graft-versus-host disease of the gut: considerations for the gastroenterologist

S Naymagon, L Naymagon, SY Wong, HM Ko… - Nature Reviews …, 2017 - nature.com
Haematopoietic stem cell transplantation (HSCT) is central to the management of many
haematological disorders. A frequent complication of HSCT is acute graft-versus-host …

Cytomegalovirus infection and the gastrointestinal tract

DM You, MD Johnson - Current gastroenterology reports, 2012 - Springer
Cytomegalovirus (CMV) infection is common worldwide, but the majority are asymptomatic.
However, during initial infection or reactivation, CMV can cause tissue-invasive end-organ …

Hematopoietic stem cell transplantation: graft versus host disease and pathology of gastrointestinal tract, liver, and lung

N Kambham, JP Higgins, U Sundram… - Advances in anatomic …, 2014 - journals.lww.com
Hematopoietic stem cell transplantation (HCT), formerly known as bone marrow
transplantation, is an integral part of treatment for many hematological malignancies. HCT is …

[HTML][HTML] Stress responses, M2 macrophages, and a distinct microbial signature in fatal intestinal acute graft-versus-host disease

SG Holtan, A Shabaneh, BC Betts, A Rashidi… - JCI insight, 2019 - ncbi.nlm.nih.gov
Steroid-refractory intestinal acute graft-versus-host disease (aGVHD) is a frequently fatal
condition, with little known about mechanisms driving failed steroid responses in gut …

Diarrhea after allogeneic stem cell transplantation: beyond graft-versus-host disease

K Robak, J Zambonelli, J Bilinski… - European Journal of …, 2017 - journals.lww.com
Diarrhea constitutes a frequent and often debilitating complication of allogeneic
hematopoietic cell transplantation (alloHCT). Especially when accompanied by jaundice …

Endoscopy in the diagnosis of intestinal graft‐versus‐host disease: Is lower endoscopy with biopsy as effective in diagnosis as upper endoscopy combined with lower …

KR Crowell, RA Patel, M Fluchel… - Pediatric blood & …, 2013 - Wiley Online Library
Background Graft‐versus‐host disease (GvHD) causes morbidity and mortality in recipients
of hematopoietic stem cell transplantation (SCT). This study assessed the distribution of …

Prevalence of graft versus host disease and cytomegalovirus infection in patients post‐haematopoietic cell transplantation presenting with gastrointestinal symptoms

A Liu, E Meyer, L Johnston, J Brown… - Alimentary …, 2013 - Wiley Online Library
Background There is lack of consensus regarding whether both upper and lower
endoscopic examinations are required for diagnosis of gastrointestinal acute graft versus …

Stepwise endoscopy based on sigmoidoscopy in evaluating pediatric graft-versus-host disease

KJ Lee, SJ Choi, HR Yang, JY Chang… - Pediatric …, 2016 - synapse.koreamed.org
Purpose The aim of our study was to establish a safe and convenient diagnostic method for
acute gastrointestinal (GI) graft-versus-host disease (GVHD) in children by determining the …

Gastrointestinal and hepatic complications

DM Hockenbery, SI Strasser… - Thomas' hematopoietic …, 2015 - Wiley Online Library
The frequency and severity of intestinal and liver complications of hematopoietic cell
transplantation (HCT) have declined steeply over the last decade. This chapter mentions …

Repeat Endoscopy Affects Patient Management in Gastrointestinal Graft-Versus-Host Disease

E Shabbir, U Farooq, B Yanes… - Clinical hematology …, 2020 - Springer
Graft versus host disease (GVHD) of the gut is associated with significant morbidity and
mortality after allogeneic hematopoietic cell transplant (allo-HCT). No guidelines exist …