In the past decade, interest in pyrazole chemistry has significatively increased mainly due to
the discovery of the interesting properties exhibited by a great number of pyrazole …

Pyrazole (Figure 1), a five-membered, two-nitrogen-containing heterocycle ring, is widely
found as the core structure in a large variety of compounds that possess important …

A novel class of anthranilic diamides has been discovered with exceptional insecticidal
activity on a range of Lepidoptera. These compounds have been found to exhibit their action …

The action of the coumarin-type drugs and related compounds is reviewed to their VKOR
antagonistic effects. In our study, twenty 3-pyridinyl, pyrimidinyl and pyrazolyl-4 …

Thrombosis is the underlying cause of a host of common, debilitating, and often fatal
cardiovascular disorders. Formation of thrombi in the arterial circulation can lead to acute …

Efforts to improve oral drug bioavailability have grown in parallel with the pharmaceutical
industry. As the number and chemical diversity of drugs has increased, new strategies have …

A general and practical strategy for 3-trifluoromethylpyrazole synthesis is reported that
occurs by the three-component coupling of environmentally friendly and large-tonnage …

A general and practical method for the synthesis of 5-trifluoromethylpyrazoles is reported
that occurs by the coupling of hydrazonyl chlorides with environmentally friendly and large …

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In the recent past trifluoromethylpyrazoles have gained much attention, particularly as anti-
inflammatory and antibacterial agents, in the field of medicinal chemistry. The location of …