The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease
The chemokine receptor CXCR4 and its ligand CXCL12 play an important homeostatic
function by mediating the homing of progenitor cells in the bone marrow and regulating their …
function by mediating the homing of progenitor cells in the bone marrow and regulating their …
Homing of endogenous stem/progenitor cells for in situ tissue regeneration: promises, strategies, and translational perspectives
FM Chen, LA Wu, M Zhang, R Zhang, HH Sun - Biomaterials, 2011 - Elsevier
Stem cell-based therapy has been one of the best documented approaches in regenerative
medicine, promising cures for a multitude of diseases and disorders. However, the ex vivo …
medicine, promising cures for a multitude of diseases and disorders. However, the ex vivo …
[HTML][HTML] Bioengineering CXCR4-overexpressing cell membrane functionalized ROS-responsive nanotherapeutics for targeting cerebral ischemia-reperfusion injury
L Luo, G Zang, B Liu, X Qin, Y Zhang, Y Chen… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: As a potentially life-threatening disorder, cerebral ischemia-reperfusion (I/R)
injury is associated with significantly high mortality, especially the irreversible brain tissue …
injury is associated with significantly high mortality, especially the irreversible brain tissue …
Chemokines in CNS injury and repair
A Jaerve, HW Müller - Cell and tissue research, 2012 - Springer
Recruitment of inflammatory cells is known to drive the secondary damage cascades that
are common to injuries of the central nervous system (CNS). Cell activation and infiltration to …
are common to injuries of the central nervous system (CNS). Cell activation and infiltration to …
Curcumin suppresses glioblastoma cell proliferation by p-AKT/mTOR pathway and increases the PTEN expression
Z Wang, F Liu, W Liao, L Yu, Z Hu, M Li, H Xia - Archives of Biochemistry …, 2020 - Elsevier
Background Glioblastoma (GB) is the most common neoplasm in the brain. Curcumin, as a
known polyphenolic compound extracted from turmeric, is a chemotherapy used in some …
known polyphenolic compound extracted from turmeric, is a chemotherapy used in some …
CC and CXC chemokines are pivotal mediators of cerebral injury in ischaemic stroke
M Mirabelli-Badenier, V Braunersreuther… - Thrombosis and …, 2011 - thieme-connect.com
The definition of ischaemic stroke has been recently updated as an acute episode of
neurological dysfunction caused by focal brain, spinal cord, or retinal ischaemia in the …
neurological dysfunction caused by focal brain, spinal cord, or retinal ischaemia in the …
The SDF-1/CXCR4 axis regulates migration of transplanted bone marrow mesenchymal stem cells towards the pancreas in rats with acute pancreatitis
J Gong, HB Meng, J Hua, ZS Song… - Molecular …, 2014 - spandidos-publications.com
Stromal cell-derived factor-1 (SDF-1) and its receptor, CXC chemokine receptor-4 (CXCR4),
are important regulators in the migration of bone marrow mesenchymal stem cells (BMSCs) …
are important regulators in the migration of bone marrow mesenchymal stem cells (BMSCs) …
Chemotactic recruitment of genetically engineered cell membrane-camouflaged metal− organic framework nanoparticles for ischemic osteonecrosis treatment
H Jiang, W Xia, T Xia, L Jiang, J Yu, X Zhu, C Lin… - Acta Biomaterialia, 2024 - Elsevier
Ischemic osteonecrosis, particularly glucocorticoid-induced osteonecrosis of the femoral
head (GIONFH), is primarily due to the dysfunction of osteogenesis and angiogenesis …
head (GIONFH), is primarily due to the dysfunction of osteogenesis and angiogenesis …
Migration of CXCR4 gene‐modified bone marrow‐derived mesenchymal stem cells to the acute injured kidney
N Liu, J Tian, J Cheng, J Zhang - Journal of cellular …, 2013 - Wiley Online Library
Bone marrow‐derived mesenchymal stem cells (BMSCs) can migrate to the injured kidney
after acute kidney injury (AKI) with limited efficiency. This study investigated the effect of …
after acute kidney injury (AKI) with limited efficiency. This study investigated the effect of …
Vasculoprotective effects of vildagliptin. Focus on atherogenesis
M Wiciński, K Górski, E Wódkiewicz, M Walczak… - International journal of …, 2020 - mdpi.com
Vildagliptin is a representative of Dipeptidyl Peptidase-4 (DPP-4) inhibitors,
antihyperglycemic drugs, approved for use as monotherapy and combination therapy in type …
antihyperglycemic drugs, approved for use as monotherapy and combination therapy in type …