Self-healing injectable hydrogels for tissue regeneration

P Bertsch, M Diba, DJ Mooney… - Chemical …, 2022 - ACS Publications
Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

Engineered biomaterials for in situ tissue regeneration

AK Gaharwar, I Singh, A Khademhosseini - Nature Reviews Materials, 2020 - nature.com
In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …

Scarless wound healing programmed by core-shell microneedles

Y Zhang, S Wang, Y Yang, S Zhao, J You… - Nature …, 2023 - nature.com
Effective reprogramming of chronic wound healing remains challenging due to the limited
drug delivery efficacy hindered by physiological barriers, as well as the inappropriate dosing …

Hydrogel‐based growth factor delivery platforms: strategies and recent advances

BH Shan, FG Wu - Advanced Materials, 2024 - Wiley Online Library
Growth factors play a crucial role in regulating a broad variety of biological processes and
are regarded as powerful therapeutic agents in tissue engineering and regenerative …

Wirelessly powered electrical-stimulation based on biodegradable 3D piezoelectric scaffolds promotes the spinal cord injury repair

P Chen, C Xu, P Wu, K Liu, F Chen, Y Chen, H Dai… - ACS …, 2022 - ACS Publications
An electroactive scaffold integrated with noninvasive in vivo electrical-stimulation (ES)
capability shows great promise in the repair and regeneration of damaged tissues …

Engineering bacteria‐activated multifunctionalized hydrogel for promoting diabetic wound healing

Y Lu, H Li, J Wang, M Yao, Y Peng, T Liu… - Advanced Functional …, 2021 - Wiley Online Library
Engineering therapeutic angiogenesis in impaired tissues is critical for chronic wound
healing. Materials can be engineered to deliver specific biological cues that enhance …

Design challenges in polymeric scaffolds for tissue engineering

MI Echeverria Molina, KG Malollari… - … in Bioengineering and …, 2021 - frontiersin.org
Numerous surgical procedures are daily performed worldwide to replace and repair
damaged tissue. Tissue engineering is the field devoted to the regeneration of damaged …

Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact

Y Gao, K Peng, S Mitragotri - Advanced Materials, 2021 - Wiley Online Library
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …

Hydrogel oxygen reservoirs increase functional integration of neural stem cell grafts by meeting metabolic demands

Y Wang, ER Zoneff, JW Thomas, N Hong… - Nature …, 2023 - nature.com
Injectable biomimetic hydrogels have great potential for use in regenerative medicine as
cellular delivery vectors. However, they can suffer from issues relating to hypoxia, including …

A tough nitric oxide-eluting hydrogel coating suppresses neointimal hyperplasia on vascular stent

Y Chen, P Gao, L Huang, X Tan, N Zhou, T Yang… - Nature …, 2021 - nature.com
Vascular stent is viewed as one of the greatest advancements in interventional cardiology.
However, current approved stents suffer from in-stent restenosis associated with neointimal …