Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a
mosquito-borne disease of major public health concern associated with significant morbidity …

Dengue is a mosquito-borne viral disease of expanding geographical range and incidence.
The existence of four viral serotypes and the association of prior dengue virus infection with …

Much remains to be learned about the pathogenesis of the different manifestations of
dengue virus (DENV) infections in humans. They may range from subclinical infection to …

Dengue viruses (DENVs) cause the most common arthropod-borne viral disease in man
with 50–100 million infections per year. Because of the lack of a vaccine and antiviral drugs …

Abstract Dengue virus (DENV 1-4) represents a major emerging arthropod-borne pathogen.
All four DENV serotypes are prevalent in the (sub) tropical regions of the world and infect 50 …

Dengue has emerged as an international public health problem. Reasons for the
resurgence of dengue in the tropics and subtropics are complex and include unprecedented …

Endothelial dysfunction leading to vascular leak is the hallmark of severe dengue. Vascular
leak typically becomes clinically evident 3–6 days after the onset of illness, which is known …

The development of animal models of dengue virus (DENV) infection and disease has been
challenging, as epidemic DENV does not naturally infect non-human species. Non-human …

Abstract Background Many countries in Asia and Latin America are currently facing a double
burden of outbreaks due to dengue and COVID-19. Here we discuss the similarities and …

Dengue viruses (DENV), a group of four serologically distinct but related flaviviruses, are the
cause of one of the most important emerging viral diseases. DENV infections result in a wide …