Breathing is a vital rhythmic motor behavior with a surprisingly broad influence on the brain
and body. The apparent simplicity of breathing belies a complex neural control system, the …

Rhythmicity is a universal timing mechanism in the brain, and the rhythmogenic mechanisms
are generally dynamic. This is illustrated for the neuronal control of breathing, a behavior …

The analgesic utility of opioid-based drugs is limited by the life-threatening risk of respiratory
depression. Opioid-induced respiratory depression (OIRD), mediated by the μ-opioid …

Respiratory depression is the proximal cause of death in opioid overdose, yet the
mechanisms underlying this potentially fatal outcome are not well understood. The goal of …

Inspiratory breathing rhythms arise from synchronized neuronal activity in a bilaterally
distributed brainstem structure known as the preBötzinger complex (preBötC). In in vitro slice …

We report a detailed analysis on the emergence of bursting in a recently developed neural
mass model that includes short-term synaptic plasticity. Neural mass models can mimic the …

This is a book about 'Neurodynamics'. What we mean is that this is a book about how ideas
from dynamical systems theory have been developed and employed in recent years to give …

The two-variable Bonhoeffer–van der Pol oscillator, which is equivalent to the FitzHugh–
Nagumo model, can be represented by a natural circuit, ie, a circuit consisting only of simple …

Mixed-mode oscillations consisting of alternating small-and large-amplitude oscillations are
increasingly well understood and are often caused by folded singularities, canard orbits, or …

Mixed-mode oscillations (MMOs) are a complex dynamical behavior in which each cycle of
oscillation consists of one or more large amplitude spikes followed by one or more small …