[HTML][HTML] Neisseria gonorrhoeae host adaptation and pathogenesis

SJ Quillin, HS Seifert - Nature Reviews Microbiology, 2018 - nature.com
The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

Male infertility: a public health issue caused by sexually transmitted pathogens

F Gimenes, RP Souza, JC Bento, JJV Teixeira… - Nature Reviews …, 2014 - nature.com
Sexually transmitted diseases (STDs) are caused by several pathogens, including bacteria,
viruses and protozoa, and can induce male infertility through multiple pathophysiological …

The Molecular Mechanisms Used by Neisseria gonorrhoeae To Initiate Infection Differ between Men and Women

JL Edwards, MA Apicella - Clinical microbiology reviews, 2004 - Am Soc Microbiol
The molecular mechanisms used by the gonococcus to initiate infection exhibit gender
specificity. The clinical presentations of disease are also strikingly different upon comparison …

The role of infections and leukocytes in male infertility

R Henkel, U Offor, D Fisher - Andrologia, 2021 - Wiley Online Library
Declining birth rates are one of the problems facing society today. Male counterparts are
responsible for about half of the infertility cases, and genitourinary tract infections may play a …

Pathogenesis of Neisseria gonorrhoeae and the Host Defense in Ascending Infections of Human Fallopian Tube

JD Lenz, JP Dillard - Frontiers in immunology, 2018 - frontiersin.org
Neisseria gonorrhoeae is an obligate human pathogen that causes mucosal surface
infections of male and female reproductive tracts, pharynx, rectum, and conjunctiva …

Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody

S Gulati, FJ Beurskens, BJ de Kreuk, M Roza… - PLoS …, 2019 - journals.plos.org
Multidrug-resistant Neisseria gonorrhoeae is a global health problem. Monoclonal antibody
(mAb) 2C7 recognizes a gonococcal lipooligosaccharide epitope that is expressed by> 95 …

Glycosylation with heptose residues mediated by the aah gene product is essential for adherence of the AIDA‐I adhesin

I Benz, MA Schmidt - Molecular microbiology, 2001 - Wiley Online Library
The diffuse adherence of Escherichia coli strain 2787 (O126: H27) is mediated by the
autotransporter adhesin AIDA‐I (a dhesin‐i nvolved‐in‐d iffuse‐a dherence) encoded by the …

Evolution of carbohydrate antigens—microbial forces shaping host glycomes?

JR Bishop, P Gagneux - Glycobiology, 2007 - academic.oup.com
Many glycans show remarkably discontinuous distribution across evolutionary lineages.
These differences play major roles when organisms belonging to different lineages interact …

Playing Dr Jekyll and Mr Hyde: combined mechanisms of phase variation in bacteria

B Hallet - Current opinion in microbiology, 2001 - Elsevier
Phase variation is the adaptive process by which bacteria undergo frequent and reversible
phenotypic changes resulting from genetic alterations in specific loci of their genomes. This …

Why Helicobacter pylori has Lewis antigens

BJ Appelmelk, MA Monteiro, SL Martin, AP Moran… - Trends in …, 2000 - cell.com
In mimicry with human gastric epithelial cells, the lipopolysaccharide of Helicobacter pylori
expresses Lewis blood group antigens. Recent data suggest that molecular mimicry does …