Cutaneous T cell lymphoma

R Dummer, MH Vermeer, JJ Scarisbrick… - Nature Reviews …, 2021 - nature.com
Primary cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of lymphomas
that present in the skin with no evidence of extracutaneous disease at the time of diagnosis …

[HTML][HTML] SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities

A Andrades, P Peinado, JC Alvarez-Perez… - Molecular cancer, 2023 - Springer
Hematological malignancies are a highly heterogeneous group of diseases with varied
molecular and phenotypical characteristics. SWI/SNF (SWItch/Sucrose Non-Fermentable) …

Naturally occurring T cell mutations enhance engineered T cell therapies

J Garcia, J Daniels, Y Lee, I Zhu, K Cheng, Q Liu… - Nature, 2024 - nature.com
Adoptive T cell therapies have produced exceptional responses in a subset of patients with
cancer. However, therapeutic efficacy can be hindered by poor T cell persistence and …

Integrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity

J Park, J Daniels, T Wartewig… - Blood, The Journal …, 2021 - ashpublications.org
Cutaneous T-cell lymphomas (CTCLs) are a clinically heterogeneous collection of
lymphomas of the skin-homing T cell. To identify molecular drivers of disease phenotypes …

[HTML][HTML] Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma

X Liu, S Jin, S Hu, R Li, H Pan, Y Liu, P Lai, D Xu… - Nature …, 2022 - nature.com
Cutaneous T cell lymphoma (CTCL) represents a heterogeneous group of non-Hodgkin
lymphoma distinguished by the presence of clonal malignant T cells. The heterogeneity of …

Mycosis fungoides and Sézary syndrome: an update

C Larocca, T Kupper - Hematology/Oncology Clinics, 2019 - hemonc.theclinics.com
Cutaneous T-cell lymphomas (CTCLs) encompass a heterogeneous collection of non-
Hodgkin lymphomas that arise from skin-tropic memory T lymphocytes. Among them …

[HTML][HTML] Molecular pathogenesis of Cutaneous T cell Lymphoma: Role of chemokines, cytokines, and dysregulated signaling pathways

K Patil, S Kuttikrishnan, AQ Khan, F Ahmad… - Seminars in Cancer …, 2022 - Elsevier
Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of lymphoproliferative
neoplasms that exhibit a wide spectrum of immune-phenotypical, clinical, and …

[HTML][HTML] Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas

J Daniels, PG Doukas, MEM Escala… - Nature …, 2020 - nature.com
Primary cutaneous γδ T cell lymphomas (PCGDTLs) represent a heterogeneous group of
uncommon but aggressive cancers. Herein, we perform genome-wide DNA, RNA, and T cell …

Overarching roles of diacylglycerol signaling in cancer development and antitumor immunity

M Cooke, MG Kazanietz - Science Signaling, 2022 - science.org
Diacylglycerol (DAG) is a lipid second messenger that is generated in response to
extracellular stimuli and channels intracellular signals that affect mammalian cell …

[图书][B] Skin lymphoma: the illustrated guide

L Cerroni - 2020 - books.google.com
A complete guide to the diagnosis and management of cutaneous lymphomas and
pseudolymphomas Easily misdiagnosed as benign skin diseases, malignant cutaneous …