Glucocorticoids and cognitive function: a walkthrough in endogenous and exogenous alterations
D De Alcubierre, D Ferrari, G Mauro, AM Isidori… - Journal of …, 2023 - Springer
Purpose The hypothalamic–pituitary–adrenal (HPA) axis exerts many actions on the central
nervous system (CNS) aside from stress regulation. Glucocorticoids (GCs) play an important …
nervous system (CNS) aside from stress regulation. Glucocorticoids (GCs) play an important …
Chronic restraint stress induces hippocampal memory deficits by impairing insulin signaling
Chronic stress is a psychologically significant factor that impairs learning and memory in the
hippocampus. Insulin signaling is important for the development and cognitive function of …
hippocampus. Insulin signaling is important for the development and cognitive function of …
The role of annexin A1 and formyl peptide receptor 2/3 signaling in chronic corticosterone-induced depression-like behaviors and impairment in hippocampal …
AF Peritore, R Crupi, M Scuto… - CNS & Neurological …, 2020 - ingentaconnect.com
Background: The activity of the Hypothalamic-Pituitary-Adrenal (HPA) axis is commonly
dysregulated in stress-related psychiatric disorders. Annexin A1 (ANXA1), an endogenous …
dysregulated in stress-related psychiatric disorders. Annexin A1 (ANXA1), an endogenous …
Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids
It is widely accepted that narcotic use during pregnancy and specific environmental factors
(eg, maternal immune activation and chronic stress) may increase risk of neuropsychiatric …
(eg, maternal immune activation and chronic stress) may increase risk of neuropsychiatric …
Neuroprotective effect of 25-Methoxyhispidol A against CCl4-induced behavioral alterations by targeting VEGF/BDNF and caspase-3 in mice
Brain oxidative stress and neuroinflammation have been implicated in various psychiatric
disorders. The current study investigated the effect and mechanism of 25-Methoxyhispidol A …
disorders. The current study investigated the effect and mechanism of 25-Methoxyhispidol A …
Txnip mediates glucocorticoid-activated NLRP3 inflammatory signaling in mouse microglia
V Bharti, H Tan, H Zhou, JF Wang - Neurochemistry international, 2019 - Elsevier
Many studies indicate that chronic stress and excessive stress hormone can cause an
inflammatory response. Thioredoxin-interacting protein (Txnip) as an endogenous …
inflammatory response. Thioredoxin-interacting protein (Txnip) as an endogenous …
Subthreshold doses of guanosine plus ketamine elicit antidepressant-like effect in a mouse model of depression induced by corticosterone: Role of GR/NF-κB/IDO-1 …
Augmentative treatment is considered the best second-option when a first-choice drug has
partial limitations, particularly by allowing antidepressant dose reduction. Considering that …
partial limitations, particularly by allowing antidepressant dose reduction. Considering that …
[HTML][HTML] Cognitive functions in children with congenital adrenal hyperplasia
NH Amr, AY Baioumi, MN Serour, A Khalifa… - … of Endocrinology and …, 2019 - SciELO Brasil
Objective There is controversy regarding cognitive function in patients with congenital
adrenal hyperplasia (CAH). This study is aimed at the assessment of cognitive functions in …
adrenal hyperplasia (CAH). This study is aimed at the assessment of cognitive functions in …
Discovery of early life stress interacting and sex‐specific quantitative trait loci impacting cocaine responsiveness
JR Bagley, KK Szumlinski… - British journal of …, 2019 - Wiley Online Library
Background and Purpose Addiction vulnerability involves complex gene X environment
interactions leading to a pathological response to drugs. Identification of the genes involved …
interactions leading to a pathological response to drugs. Identification of the genes involved …
Protective effect of Moringa oleifera Lam. leaf extract against oxidative stress, inflammation, depression, and apoptosis in a mouse model of hepatic encephalopathy
MS Mahmoud, AF El-Kott, HIM AlGwaiz… - … Science and Pollution …, 2022 - Springer
The present study aimed to assess the antioxidative, anti-inflammatory, antiapoptotic, and
anti-depression impacts of Moringa oleifera Lam. leaf ethanolic extract (MOLE) in the …
anti-depression impacts of Moringa oleifera Lam. leaf ethanolic extract (MOLE) in the …