Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …

The gasotransmitters are a family of gaseous signaling molecules which are produced
endogenously and act at specific receptors to play imperative roles in physiologic and …

In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

Nitroxyl (HNO) is a redox sibling of nitric oxide (NO) that targets distinct signalling pathways
with pharmacological endpoints of high significance in the treatment of heart failure …

Acute heart failure (HF) and in particular, cardiogenic shock are associated with high
morbidity and mortality. A therapeutic dilemma is that the use of positive inotropic agents …

Over the past century, HNO research has evolved from fundamental physical examinations
to elucidation of interactions in atmospheric, industrial and bacterial processes. Most …

Nitric oxide (NO) participates in the control of contractility and heart rate, limits cardiac
remodeling after an infarction and contributes to the protective effect of ischemic pre-and …

Historically acknowledged as toxic gases, hydrogen sulfide (H2S) and nitric oxide (NO) are
now recognized as the predominant members of a new family of signaling molecules,“ …

Until recently, most of the biological effects of nitric oxide (NO) have been attributed to its
uncharged state (NO), yet NO can also exist in the reduced state as nitroxyl (HNO or NO−) …

With respect to structural and functional cardiac disorders, heart failure (HF) is divided into
HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF) …