The gastrointestinal tract is home to the largest microbial population in the human body. The
gut microbiota plays significant roles in the development of the gut immune system and has …

Alopecia areata (AA) is an autoimmune disease that has a complex underlying
immunopathogenesis characterized by nonscarring hair loss ranging from small bald …

Background Inflammatory autoimmune arthritis like that present in rheumatoid arthritis (RA)
is treated by medications with many side effects. This study was a trial to benefit from …

Neuroinflammation is involved in the physiological and pathological processes of numerous
neurological diseases, and its inhibition seems to be a promising therapeutic direction for …

Stress-induced phosphoprotein-1 (STIP1)—a heat shock protein (HSP) 70/HSP90 adaptor
protein—is commonly overexpressed in malignant cells, where it controls proliferation via …

Abstract Janus kinase 1 (JAK1) is a key regulator of gene transcription, inhibition of JAK1 is
an intervention for many diseases including rheumatoid arthritis and Crohn's disease. In this …

Poultry is a major source of human foodborne illness caused by broad host range
Salmonella serovars (paratyphoid), and developing cost-effective, pre-harvest interventions …

Background and Aims: A compromise in intestinal mucosal functions is associated with
several chronic inflammatory diseases. Previously, we reported that obese humans have a …

The gastrointestinal (GI) tract, home to the largest microbial population in the human body,
plays a crucial role in overall health through various mechanisms. Recent advancements in …

Abstract Natriuretic peptide receptor 1 (NPR1) is conventionally known as a regulator of
vascular homeostasis. Here, we generated an Npr1 knockout mouse model with …