Analyzing free zinc(ii) ion concentrations in cell biology with fluorescent chelating molecules

W Maret - Metallomics, 2015 - academic.oup.com
Essential metal ions are tightly controlled in biological systems. An understanding of metal
metabolism and homeostasis is being developed from quantitative information of the sizes …

Zinc transporters and zinc signaling: new insights into their role in type 2 diabetes

SA Myers - International journal of endocrinology, 2015 - Wiley Online Library
Zinc is an essential trace element that plays a vital role in many biological processes
including growth and development, immunity, and metabolism. Recent studies have …

Zinc ionophore activity of quercetin and epigallocatechin-gallate: from Hepa 1-6 cells to a liposome model

H Dabbagh-Bazarbachi, G Clergeaud… - Journal of Agricultural …, 2014 - ACS Publications
Labile zinc, a tiny fraction of total intracellular zinc that is loosely bound to proteins and
easily interchangeable, modulates the activity of numerous signaling and metabolic …

Relative penetration of zinc oxide and zinc ions into human skin after application of different zinc oxide formulations

AM Holmes, Z Song, HR Moghimi, MS Roberts - ACS nano, 2016 - ACS Publications
Zinc oxide (ZnO) is frequently used in commercial sunscreen formulations to deliver their
broad range of UV protection properties. Concern has been raised about the extent to which …

Zinc drives vasorelaxation by acting in sensory nerves, endothelium and smooth muscle

AH Betrie, JA Brock, OF Harraz, AI Bush, GW He… - Nature …, 2021 - nature.com
Zinc, an abundant transition metal, serves as a signalling molecule in several biological
systems. Zinc transporters are genetically associated with cardiovascular diseases but the …

Membrane androgen receptor characteristics of human ZIP9 (SLC39A) zinc transporter in prostate cancer cells: Androgen-specific activation and involvement of an …

P Thomas, Y Pang, J Dong - Molecular and cellular endocrinology, 2017 - Elsevier
Characteristics of novel human membrane androgen receptor (mAR), ZIP9 (SLC39A9), were
investigated in ZIP9-transfected PC-3 cells (PC3-ZIP9). Ligand blot analysis showed plasma …

Zinc modulates endotoxin-induced human macrophage inflammation through ZIP8 induction and C/EBPβ inhibition

CJ Pyle, S Akhter, SY Bao, CE Dodd, LS Schlesinger… - PloS one, 2017 - journals.plos.org
Two vital functions of the innate immune system are to initiate inflammation and redistribute
micronutrients in favor of the host. Zinc is an essential micronutrient used in host defense …

Labile low-molecular-mass metal complexes in mitochondria: trials and tribulations of a burgeoning field

PA Lindahl, MJ Moore - Biochemistry, 2016 - ACS Publications
Iron, copper, zinc, manganese, cobalt, and molybdenum play important roles in
mitochondrial biochemistry, serving to help catalyze reactions in numerous metalloenzymes …

Parameters Influencing Zinc in Experimental Systems in Vivo and in Vitro

J Ollig, V Kloubert, I Weßels, H Haase, L Rink - Metals, 2016 - mdpi.com
In recent years, the role of zinc in biological systems has been a subject of intense research.
Despite wide increase in our knowledge and understanding of zinc homeostasis, numerous …

Peroxiredoxin 5 deficiency exacerbates iron overload-induced neuronal death via ER-mediated mitochondrial fission in mouse hippocampus

DG Lee, MK Kam, SR Lee, HJ Lee, DS Lee - Cell Death & Disease, 2020 - nature.com
Iron is an essential element for cellular functions, including those of neuronal cells.
However, an imbalance of iron homeostasis, such as iron overload, has been observed in …