Inflammatory bowel disease (IBD) is one of the most common diseases in the
gastrointestinal tract related to aberrant inflammation. Pyroptosis, which is characterized by …

Emerging evidence suggests that USP39 plays an important role in the development of
hepatocellular carcinoma (HCC). However, the molecular mechanism by which USP39 …

The eukaryotic pathogens Trypanosoma brucei, Trypanosoma cruzi and Leishmania are
responsible for debilitating diseases that affect millions of people worldwide. The numbers of …

Reactive oxygen species-induced vessel endothelium injury is crucial in cardiovascular
diseases progression. Rice-derived bran bioactive peptides (RBAP) might exert antioxidant …

Highlights•Ubiquitination and ubiquitin-like modification regulates trypanosomatid
differentiation.•Inventories of ubiquitination system components compiled for …

Post-translational modifications such as ubiquitination are important for orchestrating the
cellular transformations that occur as the Leishmania parasite differentiates between its …

Post-translational protein regulation allows for fine-tuning of cellular functions and involves a
wide range of modifications, including ubiquitin and ubiquitin-like modifiers (Ubls). The …

Type II diabetes is a complex, chronic, and progressive disease. Glucagon‐like peptide‐1 (7–
36) amide (GLP‐1) is a gut hormone released from the L cells which stimulate insulin …

APYRASE s, which directly regulate intra-and extra-cellular ATP homeostasis, play a pivotal
role in the regulation of various stress adaptations in mammals, bacteria and plants. In the …

Abstract < bold> Background/Aims: </bold> Type II diabetes is a complex, chronic,
and progressive disease. Glucagon-like peptide-1 (7–6) amide (GLP-1) is a gut hormone …