Translational medicine aims to improve human health by exploring potential treatment
methods developed during basic scientific research and applying them to the treatment of …

The underlying cause of cancer is genetic disruption, so gene editing technologies,
particularly CRISPR/Cas systems can be used to go against cancer. The field of gene …

Extracellular matrix (ECM) is crucial in various biological functions during tumor progression,
including induction of anoikis resistance and cell adhesion‐mediated drug resistance (CAM …

Background Lung adenocarcinoma (LUAD) is the most prevalent histotype of non‐small cell
lung cancer. Anoikis, an alternative form of programmed cell death, plays a pivotal role in …

The Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated
protein 9 (CRISPR/Cas9) system, an RNA-based adaptive immune system found in bacteria …

Anoikis, a form of apoptotic cell death resulting from inadequate cell-matrix interactions, has
been implicated in tumor progression by regulating tumor angiogenesis and metastasis …

Colorectal cancer (CRC) is one of the most lethal cancers. Single-cell RNA sequencing
(scRNA-seq) and protein-protein interactions (PPIs) have enabled the systematic study of …

CXCL8 is the most representative chemokine produced autocrine or paracrine by tumor
cells, endothelial cells and lymphocytes. It can play a key role in normal tissues and tumors …

Background: Tumor pathology can assess patient prognosis based on a morphological
deviation of tumor tissue from normal. Digitizing whole slide images (WSIs) of tissue enables …

Chemotherapy is a critical treatment for endocrine-related cancers; however,
chemoresistance and disease recurrence remain a challenge. The interplay between cancer …