This Perspective proposes definitions for key terms in the field of HIV-1 latency and
eradication. In the context of eradication, a reservoir is a cell type that allows persistence of …

Life expectancy living with HIV: recent estimates and future... : Current Opinion in Infectious
Diseases Life expectancy living with HIV: recent estimates and future implications : Current …

Background Long-acting injectable regimens may simplify therapy for patients with human
immunodeficiency virus type 1 (HIV-1) infection. Methods We conducted a phase 3 …

Background Cabotegravir and rilpivirine are antiretroviral drugs in development as long-
acting injectable formulations. The LATTE-2 study evaluated long-acting cabotegravir plus …

This report updates and combines earlier versions of guidelines for the prevention and
treatment of opportunistic infections (OIs) in HIV-infected adults (ie, persons aged> 18 years) …

BACKGROUND: Combination antiretroviral therapy has led to significant increases in
survival and quality of life, but at a population-level the effect on life expectancy is not well …

Countries in sub-Saharan Africa were once dismissed by Western experts as being too poor
and chaotic to benefit from the antiretroviral drugs that transformed the AIDS epidemic in the …

Background Results of cohort studies and mathematical models have suggested that
increased coverage with highly active antiretroviral therapy (HAART) could reduce HIV …

Methods: A stochastic computer simulation model of HIV infection and the effect of ART was
used to estimate life expectancy and determine the distribution of potential lifetime outcomes …

In the last 25 years, HIV-1, the retrovirus responsible for the acquired immunodeficiency
syndrome (AIDS), has gone from being an “inherently untreatable” infectious agent to one …