Asymmetric catalysis mediated by synthetic peptides, version 2.0: expansion of scope and mechanisms

AJ Metrano, AJ Chinn, CR Shugrue, EA Stone… - Chemical …, 2020 - ACS Publications
Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Organocatalytic activation of hydrogen peroxide: towards green and sustainable oxidations

ET Poursaitidis, PL Gkizis, I Triandafillidi… - Chemical …, 2024 - pubs.rsc.org
The advent of organocatalysis provided an additional option in every researcher's arsenal,
towards the development of elegant and sustainable protocols for various organic …

Optical analysis of reaction yield and enantiomeric excess: a new paradigm ready for prime time

BT Herrera, SL Pilicer, EV Anslyn… - Journal of the …, 2018 - ACS Publications
This Perspective highlights the advances of optical methods for asymmetric reaction
discovery. Optical analysis allows for the determination of absolute configuration …

Circular dichroism sensing: Strategies and applications

JSSK Formen, JR Howard, EV Anslyn… - Angewandte Chemie …, 2024 - Wiley Online Library
The analysis of the absolute configuration, enantiomeric composition, and concentration of
chiral compounds are frequently encountered tasks across the chemical and health …

Molecularly thin, two-dimensional all-organic perovskites

HS Choi, J Lin, G Wang, WPD Wong, IH Park, F Lin… - Science, 2024 - science.org
Recently, the emergence of all-organic perovskites with three-dimensional (3D) structures
has expanded the potential applications of perovskite materials. However, the synthesis and …

A Data-Driven Approach to the Development and Understanding of Chiroptical Sensors for Alcohols with Remote γ-Stereocenters

JJ Dotson, EV Anslyn, MS Sigman - Journal of the American …, 2021 - ACS Publications
Dynamic covalent chemistry-based sensors have recently emerged as powerful tools to
rapidly determine the enantiomeric excess of organic small molecules. While a bevy of …

High-throughput determination of enantiopurity by microplate circular dichroism

SL Pilicer, JM Dragna, A Garland… - The Journal of …, 2020 - ACS Publications
Methods for the rapid determination of enantiomeric excess (ee) in asymmetric synthetic
methodology development are increasingly in demand as high-throughput experimentation …

Click chemistry enables quantitative chiroptical sensing of chiral compounds in protic media and complex mixtures

FY Thanzeel, K Balaraman, C Wolf - Nature communications, 2018 - nature.com
Click reactions have become powerful synthetic tools with unique applications in the health
and materials sciences. Despite the progress with optical sensors that exploit the principles …

Optical chirality sensing with an auxiliary‐free earth‐abundant cobalt probe

ZA De los Santos, CC Lynch… - Angewandte Chemie …, 2019 - Wiley Online Library
Broadly useful chiroptical enantiomeric excess (ee) sensing remains challenging and
typically involves carefully designed molecular receptors or supramolecular assemblies …

Rapid optical determination of enantiomeric excess, diastereomeric excess, and total concentration using dynamic-covalent assemblies: A demonstration using 2 …

BT Herrera, SR Moor, M McVeigh… - Journal of the …, 2019 - ACS Publications
Optical analysis of reaction parameters such as enantiomeric excess (ee), diastereomeric
excess (de), and yield are becoming increasingly useful as assays for differing functional …