Significant experimental, computational, and theoretical work has identified rich structure
within the coordinated activity of interconnected neural populations. An emerging challenge …

The loss of a limb or paralysis resulting from spinal cord injury has devastating
consequences on quality of life. One approach to restoring lost sensory and motor abilities in …

Background Paralysis or amputation of an arm results in the loss of the ability to orient the
hand and grasp, manipulate, and carry objects, functions that are essential for activities of …

Paralysis following spinal cord injury, brainstem stroke, amyotrophic lateral sclerosis and
other disorders can disconnect the brain from the body, eliminating the ability to perform …

Visuomotor adaptation has been thought to be an implicit process that results when a
sensory-prediction error signal is used to update a forward model. A striking feature of …

Learning, whether motor, sensory or cognitive, requires networks of neurons to generate
new activity patterns. As some behaviours are easier to learn than others,, we asked if some …

Behavior is driven by coordinated activity across a population of neurons. Learning requires
the brain to change the neural population activity produced to achieve a given behavioral …

Learning has been associated with changes in the brain at every level of organization.
However, it remains difficult to establish a causal link between specific changes in the brain …

Sleep has been implicated in both memory consolidation and forgetting of experiences.
However, it is unclear what governs the balance between consolidation and forgetting. Here …

The brain's remarkable ability to learn and execute various motor behaviours harnesses the
capacity of neural populations to generate a variety of activity patterns. Here we explore …