Particle design via spherical agglomeration is a size enlargement technique used in various
bulk and fine chemical industries, with recent interest extending into pharmaceuticals, in …

Crystal engineering provides a rational approach to solving formulation, processing and
product performance problems. This review discusses how the concept of crystal …

The aim of this work is to study the effect of the presence of different monovalent ions (Na+,
NH 4+ and K+) on the nucleation and growth rates of CaCO 3 precipitation. There is …

Of utmost importance in the crystallization of active pharmaceutical ingredients (APIs) in the
pharmaceutical industry is to produce crystals of good physical, processing, and …

The morphological characterization of aggregates or agglomerates using image analysis is
an increasingly active area of research, whether in the chemical, environmental or civil …

Combining celecoxib with other chemopreventive drugs is a promising method of
chemoprevention for cancer, especially for colorectal cancer. However, the traditional drug …

Vanillin is a natural flavor and is widely used in the fields of medicine, food and
optoelectronics. However, the stable form I of vanillin usually shows needle or fiber-like …

This paper deals with the development of a method for spherical crystallization of benzoic
acid. Benzoic acid is dissolved in ethanol, water is used as anti-solvent and chloroform is …

Spherical agglomerates of an active pharmaceutical ingredient, ferulic acid (FA), were
prepared using four different spherical crystallization methods, ie, quasi-emulsion solvent …

Spherical crystallization of drugs is the process of obtaining larger particles by
agglomeration during crystallization. The most common techniques used to obtain such …