Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older
people, which severely impairs patients' quality of life. In the recent years, the number of …

Neuroinflammation is thought to contribute to Alzheimer's disease (AD) pathogenesis that is,
to a large extent, mediated by microglia. Given the tight interaction between the immune …

Aims As one of the most fundamental questions in modern science,“what causes
schizophrenia (SZ)” remains a profound mystery due to the absence of objective gene …

In our study, we explored changes in the redox status and inflammatory response in the
testes of the SAMP8 model of varying ages (2, 4, 8, 10 months old) compared with control …

Background: Aging and its complications such as Alzheimer's disease (AD) are associated
with chronic low-grade inflammation entitled age-associated inflammation. However, the …

Background Accumulating evidence implicates the neuroendocrine immunomodulation
(NIM) network in the physiopathological mechanism of Alzheimer's disease (AD). Notably …

Abstract Testicular Leydig cells (LCs) are the primary source of circulating androgen in men.
As men age, circulating androgen levels decline. However, whether reduced LC …

Ionizing radiation, including X and gamma rays, are used for various purposes such as;
medicine, nuclear power, research, manufacturing, food preservation and construction …

LW-AFC is a new formula derived from the Liuwei Dihuang decoction, a classical traditional
Chinese medicine prescription. Based on our research, LW-AFC is a promising drug for …

Molecular chaperon SERPINA3 colocalizes with accumulated amyloid peptide in
Alzheimer's disease (AD) patient's brain. From the QTL analysis, we narrowed down …