Candida Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents

C Spampinato, D Leonardi - BioMed research international, 2013 - Wiley Online Library
The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …

Biguanides: Species with versatile therapeutic applications

D Kathuria, AD Raul, P Wanjari, PV Bharatam - European Journal of …, 2021 - Elsevier
Biguanides are compounds in which two guanidine moieties are fused to form a highly
conjugated system. Biguanides are highly basic and hence they are available as salts …

Copper nanoparticles encapsulated in reduced graphene oxide electrode (CuxrGO1-x) for the electrochemical quantification of metformin in water

YJ Shih, YQ Su, WH Chen, SK Lin, YC He… - Chemical Engineering …, 2023 - Elsevier
Electrochemical oxidation of anti-diabetic metformin (MTF) drug was studied on glassy
carbon electrode (GCE) prepared by electroplating of copper nanoparticles (Cu NPs) on …

[HTML][HTML] Metal complexes—a promising approach to target biofilm associated infections

R Olar, M Badea, MC Chifiriuc - Molecules, 2022 - mdpi.com
Microbial biofilms are represented by sessile microbial communities with modified gene
expression and phenotype, adhered to a surface and embedded in a matrix of self-produced …

[HTML][HTML] Biological properties of transition metal complexes with metformin and its analogues

DA Rusanov, J Zou, MV Babak - Pharmaceuticals, 2022 - mdpi.com
Metformin is a widely prescribed medication for the treatment and management of type 2
diabetes. It belongs to a class of biguanides, which are characterized by a wide range of …

[HTML][HTML] Decavanadate salts of cytosine and metformin: a combined experimental-theoretical study of potential metallodrugs against diabetes and cancer

E Sánchez-Lara, S Treviño, BL Sánchez-Gaytán… - Frontiers in …, 2018 - frontiersin.org
Cytosine, a DNA and RNA building-block, and Metformin, the most widely prescribed drug
for the treatment of Type 2 Diabetes mellitus were made to react separately with ammonium …

[HTML][HTML] Metal complex formation and anticancer activity of Cu (I) and Cu (II) complexes with metformin

S Abdelrahman, M Alghrably, M Campagna… - Molecules, 2021 - mdpi.com
Metformin has been used for decades in millions of type 2 diabetes mellitus patients. In this
time, correlations between metformin use and the occurrence of other disorders have been …

[HTML][HTML] Facile fabrication and characterization of chitosan-based zinc oxide nanoparticles and evaluation of their antimicrobial and antibiofilm activity

GS Dhillon, S Kaur, SK Brar - International Nano Letters, 2014 - Springer
The present investigation deals with the facile synthesis and characterization of chitosan
(CTS)-based zinc oxide (ZnO) nanoparticles (NPs) and their antimicrobial activities against …

“What's in a structure?” The story of biguanides

D Kathuria, AA Bankar, PV Bharatam - Journal of Molecular Structure, 2018 - Elsevier
Biguanides are a very interesting class of molecules which have been extensively studied
for their medicinal applications. The structural and electronic structural aspects of …

Biodegradable copper–metformin nanoscale coordination polymers for enhanced chemo/chemodynamic synergistic therapy by reducing oxygen consumption to …

X Meng, X Zhang, Y Lei, D Cao, Z Wang - Journal of Materials …, 2021 - pubs.rsc.org
Chemo/chemodynamic synergistic therapy is a promising strategy to improve the antitumor
effect. However, hypoxia and a limited amount of hydrogen peroxide (H2O2) in the tumor …