Chronic obstructive pulmonary disease (COPD) is a global health problem, and since 2001,
the Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published its strategy …

Chronic obstructive pulmonary disease (COPD) remains a major public health problem. It is
the fourth leading cause of chronic morbidity and mortality in the United States, and is …

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive
Pulmonary Disease | NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) …

Introduction Pressure-support ventilation, is widely used in critically ill patients; however, the
relative contribution of patient's effort during assisted breathing is difficult to measure in …

The heme oxygenases, which consist of constitutive and inducible isozymes (HO-1, HO-2),
catalyze the rate-limiting step in the metabolic conversion of heme to the bile pigments (ie …

ContextThe outcome of patients receiving mechanical ventilation for particular indications
has been studied, but the outcome in a large number of unselected, heterogeneous patients …

ContextThe optimal duration of antimicrobial treatment for ventilator-associated pneumonia
(VAP) is unknown. Shortening the length of treatment may help to contain the emergence of …

Context Tracheotomy is used to replace endotracheal intubation in patients requiring
prolonged ventilation; however, there is considerable variability in the time considered …

Acute respiratory distress syndrome and acute lung injury are well defined and readily
recognised clinical disorders caused by many clinical insults to the lung or because of …

Background The need for reintubation after extubation and discontinuation of mechanical
ventilation is not uncommon and is associated with increased mortality. Noninvasive positive …