It is broadly acknowledged that the onset of dementia in Alzheimer's disease (AD) may be
modifiable by the management of risk factors. While several recent guidelines and …

Many lines of evidence have indicated the therapeutic potential of rescuing mitochondrial
integrity by targeting specific mitochondrial quality control pathways in neurodegenerative …

The irreversible and progressive neurodegenerative Alzheimer's disease (AD) is
characterized by cognitive decline, extracellular β-amyloid peptide accumulation, and tau …

Alzheimer's disease (AD) is a multifactorial pathology characterized by β-amyloid (Aβ)
deposits, Tau hyperphosphorylation, neuroinflammatory response, and cognitive deficit …

Given the failure to develop disease-modifying therapies for Alzheimer's disease (AD),
strategies aiming at preventing or delaying the onset of the disease are being prioritized …

Recently there is increasing concern over the association between sleep deprivation (S-
Dep) and depression. Mounting evidence suggests that S-Dep might be a risk factor for …

Introduction Worldwide, approximately 50 million people have dementia, with Alzheimer
disease (AD) being the most common type, accounting for 60%-70% of cases. Given its high …

Alzheimer disease (AD) is the most prevalent form of dementia among elderly people.
Owing to its varied and multicausal etiopathology, intervention strategies have been highly …

Aging, polypharmacy (concurrent use of≥ 5 medications), and functional impairment are
global healthcare challenges. However, knowledge of the age/sex-specific effects of …

Circadian rhythm disturbance (CRD) is one of the iconic manifestations in Alzheimer's
disease (AD), a disease tightly associated with age, but the characteristics and gender …